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https://hdl.handle.net/2440/101883
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Type: | Journal article |
Title: | New drugs for HDL-C disorders: the beginning |
Author: | Duong, M. Nicholls, S. |
Citation: | Current Medicinal Chemistry, 2014; 21(25):2947-2951 |
Publisher: | Bentham Science Publishers |
Issue Date: | 2014 |
ISSN: | 0929-8673 1875-533X |
Statement of Responsibility: | MyNgan Duong and Stephen J. Nicholls |
Abstract: | For more than 20 years there has been increasing interest in the development of novel therapies to raise levels of high-density lipoprotein cholesterol (HDL-C). However, well publicized failures of recent clinical trials of agents that raise HDL-C levels have stimulated considerable controversy with regard to the potential clinical utility of this therapeutic target. A number of classes of agents are currently under investigation with variable effects on HDL quantity and quality. These will be reviewed. |
Keywords: | Atherosclerosis; cardiovascular disease; HDL; lipids; risk factors |
Rights: | © 2016 Bentham Science Publishers |
DOI: | 10.2174/0929867321666140414104130 |
Published version: | http://dx.doi.org/10.2174/0929867321666140414104130 |
Appears in Collections: | Aurora harvest 3 Medicine publications |
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