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https://hdl.handle.net/2440/11364
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Type: | Journal article |
Title: | The citropin peptides from the skin glands of the Australian Blue Mountains tree frog Litoria citropa. Part 2: sequence determination using electrospray mass spectrometry |
Author: | Wabnitz, P. Bowie, J. Wallace, J. Tyler, M. |
Citation: | Rapid Communications in Mass Spectrometry, 1999; 13(17):1724-1732 |
Publisher: | John Wiley |
Issue Date: | 1999 |
ISSN: | 0951-4198 1097-0231 |
Abstract: | A combination of electrospray mass spectrometry, Lys-C digest/mass spectrometry and automated Edman sequencing provides the amino acid sequences of nineteen citropin peptides isolated from the granular dorsal and submental glands of the Blue Mountains tree frog Litoria citropa. Citropin 1.1 [Gly Leu Phe Asp Val Ile Lys Lys Val Ala Ser Val Ile Gly Gly Leu (NH(2))] and citropin 1.2 [Gly Leu Phe Asp Ile Ile Lys Lys Val Ala Ser Val Val Gly Gly Leu (NH(2))] are the two major skin peptides: both show significant wide-spectrum antibacterial activity. |
Keywords: | Skin Animals Anura Peptides Antimicrobial Cationic Peptides Amphibian Proteins Sequence Analysis Amino Acid Sequence Molecular Sequence Data Australia Mass Spectrometry |
Rights: | Copyright © 1999 John Wiley & Sons, Ltd. |
DOI: | 10.1002/(SICI)1097-0231(19990915)13:17<1724::AID-RCM706>3.0.CO;2-T |
Published version: | http://dx.doi.org/10.1002/(sici)1097-0231(19990915)13:17%3C1724::aid-rcm706%3E3.0.co;2-t |
Appears in Collections: | Aurora harvest 7 Biochemistry publications |
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