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https://hdl.handle.net/2440/114312
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DC Field | Value | Language |
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dc.contributor.author | Dawson, R. | - |
dc.contributor.author | Mcleod, D. | - |
dc.contributor.author | Koerber, J. | - |
dc.contributor.author | Plummer, J. | - |
dc.contributor.author | Dracopoulos, G. | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | Anaesthesia, 2016; 71(3):285-290 | - |
dc.identifier.issn | 0003-2409 | - |
dc.identifier.issn | 1365-2044 | - |
dc.identifier.uri | http://hdl.handle.net/2440/114312 | - |
dc.description.abstract | We used 20 ml ropivacaine 0.75% for ankle blocks before foot surgery in 90 participants who we allocated in equal numbers to: perineural dexamethasone 8 mg and intravenous saline 0.9%; perineural saline 0.9% and intravenous dexamethasone 8 mg; or perineural and intravenous saline 0.9%. Dexamethasone increased the median (IQR [range]) time for the return of some sensation or movement, from 14.6 (10.8-18.8 [5.5-38.0]) h with saline to 24.1 (19.3-29.3 [5.0-44.0]) h when given perineurally, p = 0.00098, and to 20.9 (18.3-27.8 [8.8-31.3]) h when given intravenously, p = 0.0067. Dexamethasone increased the median (IQR [range]) time for the return of normal neurology, from 17.6 (14.0-21.0 [9.5-40.5]) h with saline to 27.5 (22.0-36.3 [7.0-53.0]) h when given perineurally, p = 0.00016, and to 24.0 (20.5-32.3 [13.0-42.5]) h when given intravenously, p = 0.0022. Dexamethasone did not affect the rates of block success, postoperative pain scores, analgesic use, or nausea and vomiting. The route of dexamethasone administration did not alter its effects. | - |
dc.description.statementofresponsibility | R. L. Dawson, D. H. McLeod, J. P. Koerber, J. L. Plummer, G. C. Dracopoulos | - |
dc.language.iso | en | - |
dc.publisher | Wiley-Blackwell | - |
dc.rights | © 2015 The Association of Anaesthetists of Great Britain and Ireland | - |
dc.source.uri | http://dx.doi.org/10.1111/anae.13346 | - |
dc.subject | Foot | - |
dc.subject | Humans | - |
dc.subject | Pain, Postoperative | - |
dc.subject | Sodium Chloride | - |
dc.subject | Amides | - |
dc.subject | Dexamethasone | - |
dc.subject | Anesthetics, Local | - |
dc.subject | Glucocorticoids | - |
dc.subject | Anesthesia Recovery Period | - |
dc.subject | Time Factors | - |
dc.subject | Adult | - |
dc.subject | Aged | - |
dc.subject | Aged, 80 and over | - |
dc.subject | Middle Aged | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.subject | Ropivacaine | - |
dc.title | A randomised controlled trial of perineural vs intravenous dexamethasone for foot surgery | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1111/anae.13346 | - |
pubs.publication-status | Published | - |
Appears in Collections: | Aurora harvest 3 Medicine publications |
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