Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/117721
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dc.contributor.author | Pavathuparambil Abdul Manaph, N. | - |
dc.contributor.author | Al-Hawaas, M. | - |
dc.contributor.author | Bobrovskaya, L. | - |
dc.contributor.author | Coates, P.T. | - |
dc.contributor.author | Zhou, X.F. | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Stem Cell Research and Therapy, 2018; 9(1):189-1-189-12 | - |
dc.identifier.issn | 1757-6512 | - |
dc.identifier.issn | 1757-6512 | - |
dc.identifier.uri | http://hdl.handle.net/2440/117721 | - |
dc.description | Corrected by: Correction to: Urine-derived cells for human cell therapy (Stem Cell Res Ther. (2018) 9 (189) DOI: 10.1186/s13287-018-0932-z). The original article [1] contained a small typo affecting the co-author, Mohammed Al-Hawwas's name. This error has now been corrected. | - |
dc.description.abstract | Desirable cells for human cell therapy would be ones that can be generated by simple isolation and culture techniques using a donor sample obtained by non-invasive methods. To date, the different donor-specific cells that can be isolated from blood, skin, and hair require invasive methods for sample isolation and incorporate complex and costly reagents to culture. These cells also take considerable time for their in-vitro isolation and expansion. Previous studies suggest that donor-derived cells, namely urine stem cells and renal cells, may be isolated from human urine samples using a cost-effective and simple method of isolation, incorporating not such complex reagents. Moreover, the isolated cells, particularly urine stem cells, are superior to conventional stem cell sources in terms of favourable gene profile and inherent multipotent potential. Transdifferentiation or differentiation of human urine-derived cells can generate desirable cells for regenerative therapy. In this review, we intended to discuss the characteristics and therapeutic applications of urine-derived cells for human cell therapy. Conclusively, with detailed study and optimisation, urine-derived cells have a prospective future to generate functional lineage-specific cells for patients from a clinical translation point of view. | - |
dc.description.statementofresponsibility | Nimshitha Pavathuparambil Abdul Manaph, Mohammed Al-Hawwas, Larisa Bobrovskaya, Patrick T. Coates and Xin-Fu Zhou | - |
dc.language.iso | en | - |
dc.publisher | BMC | - |
dc.rights | © The Author(s). 2018. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | - |
dc.source.uri | http://dx.doi.org/10.1186/s13287-018-0932-z | - |
dc.subject | Differentiation | - |
dc.subject | Renal cells | - |
dc.subject | Stem cells | - |
dc.subject | Therapy | - |
dc.subject | Urine | - |
dc.title | Urine-derived cells for human cell therapy | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1186/s13287-018-0932-z | - |
dc.relation.grant | NHMRC | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Zhou, X.F. [0000-0002-8687-0175] | - |
Appears in Collections: | Aurora harvest 8 Medicine publications |
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File | Description | Size | Format | |
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hdl_117721.pdf | Published version | 4.74 MB | Adobe PDF | View/Open |
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