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https://hdl.handle.net/2440/118485
Type: | Journal article |
Title: | Patients' perspective in the decision and reimbursement process for direct-acting oral anticoagulants for atrial fibrillation and venous thromboembolic disease |
Author: | Brouwers, J. Hendriks, J. Van Laarhoven, H. Jukema, G. Pronk, M. |
Citation: | Pharmaceutisch weekblad, 2015; 150(16):72-78 |
Publisher: | LoginRadius |
Issue Date: | 2015 |
ISSN: | 0031-6911 |
Statement of Responsibility: | J.R.B.J. Brouwers, Jeroen M L Hendriks, Hans van Laarhoven, G.J. Jukema |
Abstract: | OBJECTIVE: To develop a method to incorporate practice-based knowledge of medical doctors, pharmacists, nurses and patients in treatment guidelines and in reimbursement decisions. DESIGN AND METHODS: Based on literature review and expert opinion of medical professionals a decision tree is developed for assessment of DOACs from patients' perspective in the treatment of non-valvular atrial fibrillation [nvAF] and venous thromboembolic disease (VTE). RESULTS: For both nvAF and VTE six relevant patient aspects were identified: target INR, safe use, therapy compliance, organisation of care, wellbeing and self-management. When comparing DOACs with standard VKA-containing treatment for these conditions, DOACs showed added value regarding four patient aspects in nvAF and five aspects in VTE. As an example, relevant aspects for DOACs are: easy dosage regimen, self-management of drug use and wellbeing. None of these aspects are represented in the current decision process for guidelines and reimbursement. CONCLUSION: Dealing with relevant criteria from a patients' perspective in a decision tree, DOACs have potential added value that should be considered in guideline development and reimbursement decisions. |
Rights: | Copyright status unknown |
Published version: | https://www.researchgate.net/publication/282273628_Patients'_perspective_in_the_decision_and_reimbursement_process_for_direct-acting_oral_anticoagulants_for_atrial_fibrillation_and_venous_thromboembolic_disease |
Appears in Collections: | Aurora harvest 8 Pharmacology publications |
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