Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/130190
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Type: | Journal article |
Title: | Challenges in vaccinating layer hens against salmonella typhimurium |
Author: | Jia, S. McWhorter, A.R. Andrews, D.M. Underwood, G.J. Chousalkar, K.K. |
Citation: | Vaccines, 2020; 8(4):696-696 |
Publisher: | MDPI |
Issue Date: | 2020 |
ISSN: | 2076-393X 2076-393X |
Statement of Responsibility: | Siyuan Jia, Andrea R. McWhorter, Daniel M. Andrews, Gregory J. Underwood and Kapil K. Chousalkar |
Abstract: | Salmonella Typhimurium is among the most common causes of bacterial foodborne gastrointestinal disease in humans. Food items containing raw or undercooked eggs are frequently identified during traceback investigation as the source of the bacteria. Layer hens can become persistently infected with Salmonella Typhimurium and intermittently shed the bacteria over the course of their productive lifetime. Eggs laid in a contaminated environment are at risk of potential exposure to bacteria. Thus, mitigating the bacterial load on farms aids in the protection of the food supply chain. Layer hen producers use a multifaceted approach for reducing Salmonella on farms, including the all-in-all-out management strategy, strict biosecurity, sanitization, and vaccination. The use of live attenuated Salmonella vaccines is favored because they elicit a broader host immune response than killed or inactivated vaccines that have been demonstrated to provide cross-protection against multiple serovars. Depending on the vaccine, two to three doses of Salmonella Typhimurium vaccines are generally administered to layer hens within the first few weeks. The productive life of a layer hen, however, can exceed 70 weeks and it is unclear whether current vaccination regimens are effective for that extended period. The objective of this review is to highlight layer hen specific challenges that may affect vaccine efficacy. |
Keywords: | Salmonella Typhimurium; layer hen; vaccine |
Rights: | © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
DOI: | 10.3390/vaccines8040696 |
Grant ID: | http://purl.org/au-research/grants/arc/L190100864 |
Published version: | http://dx.doi.org/10.3390/vaccines8040696 |
Appears in Collections: | Animal and Veterinary Sciences publications Aurora harvest 4 |
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