Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/13267
Citations
Scopus Web of ScienceĀ® Altmetric
?
?
Type: Journal article
Title: Enhanced fetal growth in sheep administered progesterone during the first three days of pregnancy
Author: Kleeman, D.
Walker, S.
Seamark, R.
Citation: Journal of Reproduction and Fertility, 1994; 102(2):411-417
Publisher: Blackwell Scientific Publications
Issue Date: 1994
ISSN: 0022-4251
1741-7899
Abstract: Two experiments were conducted to determine whether administration of progesterone during early pregnancy affects fetal growth in sheep and if any effect is specific to the days of treatment. In the first experiment, Merino ewes were randomly allocated to four treatment groups and inseminated at a synchronized oestrus. Three groups received progesterone on days 1-3, 3-6 or 1-6 of pregnancy while the fourth group was untreated. Concentrations of progesterone in peripheral plasma increased (P < 0.05) in all treatment groups. Fetal growth (to day 74) was greater in all treatment groups than in the control group (P < 0.001) and was greatest when treatments started on day 1. Pregnancy rate was not affected by progesterone treatment on days 3-6, but was reduced (P < 0.05) when treatment began on day 1. In the second experiment, embryos that had been exposed to either a normal (control) or a high concentration of progesterone on days 1-3 were randomly transferred, within groups, to recipient ewes that had or had not been treated with progesterone on days 1-3. In another group, embryos were exposed to a high concentration of progesterone on days 1-3 and the oviducts of the ewe were ligated. An increase in fetal mass was observed in the recipient group that had been treated with progesterone (P < 0.01) but was not observed in the initial group treated with progesterone. A greater fetal mass was also obtained when embryos that had been ligated in the oviducts of ewes treated with progesterone (P < 0.05) were transferred.(ABSTRACT TRUNCATED AT 250 WORDS)
Keywords: Fallopian Tubes; Fetus; Animals; Sheep; Progesterone; Crown-Rump Length; Embryo Transfer; Ligation; Embryonic and Fetal Development; Gestational Age; Pregnancy; Litter Size; Female
RMID: 0030003762
DOI: 10.1530/jrf.0.1020411
Appears in Collections:Agriculture, Food and Wine publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.