1. Adelaide Research & Scholarship
  2. Schools and Disciplines
  3. School of Molecular and Biomedical Science
  4. Biochemistry
  5. Biochemistry publications
Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/132974
Citations
Scopus Web of Science® Altmetric
?
?
Full metadata record
DC FieldValueLanguage
dc.contributor.authorHuang, Z.-
dc.contributor.authorKing, A.P.-
dc.contributor.authorLovett, J.-
dc.contributor.authorLai, B.-
dc.contributor.authorWoods, J.J.-
dc.contributor.authorHarris, H.H.-
dc.contributor.authorWilson, J.J.-
dc.date.issued2021-
dc.identifier.citationChemical Communications, 2021; 57(85):11189-11192-
dc.identifier.issn1359-7345-
dc.identifier.issn1364-548X-
dc.identifier.urihttps://hdl.handle.net/2440/132974-
dc.description.abstractThe photophysical and photochemical properties of two Pt(IV)Re(I) conjugates were studied via both experimental and computational methods. Both conjugates exhibit modest photocytotoxicity against ovarian cancer cells. X-ray fluorescence microscopy showed that Pt and Re colocalize in cells whether they had been irradiated or not. This work demonstrates the potential of photoactivated multilimetallic agents for combating cancer.-
dc.description.statementofresponsibilityZhouyang Huang, A. Paden King, James Lovett, Barry Lai, Joshua J. Woods, Hugh H. Harris and Justin J. Wilson-
dc.language.isoen-
dc.publisherRoyal Society of Chemistry-
dc.rightsThis journal is © The Royal Society of Chemistry 2021-
dc.source.urihttp://dx.doi.org/10.1039/d1cc04669a-
dc.subjectHela Cells-
dc.subjectHumans-
dc.subjectOvarian Neoplasms-
dc.subjectPlatinum-
dc.subjectRhenium-
dc.subjectAntineoplastic Agents-
dc.subjectPhotochemotherapy-
dc.subjectSpectrometry, X-Ray Emission-
dc.subjectDrug Screening Assays, Antitumor-
dc.subjectComputational Biology-
dc.subjectApoptosis-
dc.subjectCell Membrane Permeability-
dc.subjectLight-
dc.subjectFemale-
dc.subjectCoordination Complexes-
dc.subjectOptical Imaging-
dc.titlePhotochemistry and in vitro anticancer activity of Pt(IV)Re(I) conjugates-
dc.typeJournal article-
dc.identifier.doi10.1039/d1cc04669a-
dc.relation.granthttp://purl.org/au-research/grants/arc/DP210102148-
pubs.publication-statusPublished-
dc.identifier.orcidLovett, J. [0000-0003-1075-8619]-
dc.identifier.orcidHarris, H.H. [0000-0002-3472-8628]-
Appears in Collections:Biochemistry publications

Files in This Item:
There are no files associated with this item.
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.