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Results 11-20 of 20 (Search time: 0.005 seconds).
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Issue Date
Title
Author(s)
2008
Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexiline
Davies, B.
;
Herbert, M.
;
Coller, J.
;
Somogyi, A.
;
Milne, R.
;
Sallustio, B.
2007
Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemia
Inglis, S.
;
Herbert, M.
;
Davies, B.
;
Coller, J.
;
James, H.
;
Horowitz, J.
;
Morris, R.
;
Milne, R.
;
Somogyi, A.
;
Sallustio, B.
1998
Quantification of flunitrazepam's oxidative metabolites, 3-hydroxyflunitrazepam and desmethylflunitrazepam, in hepatic microsomal incubations by high performance liquid chromatography.
Coller, J.
;
Somogyi, A.
;
Bochner, F.
1999
Flunitrazepam oxidative metabolism in human liver microsomes: involvement of CYP2C19 and CYP3A4
Coller, J.
;
Somogyi, A.
;
Bochner, F.
2006
ABCB1 genetic variability and methadone dosage requirements in opioid-dependent individuals
Coller, J.
;
Barratt, D.
;
Dahlen, K.
;
Loennechen, M.
;
Somogyi, A.
2004
Clinical inhibition of CYP2D6-catalysed metabolism by the antianginal agent perhexiline
Davies, B.
;
Coller, J.
;
James, H.
;
Gillis, D.
;
Somogyi, A.
;
Horowitz, J.
;
Morris, R.
;
Sallustio, B.
1997
Association between CYP2C19 genotype and proguanil oxidative polymorphism.
Coller, J.
;
Somogyi, A.
;
Bochner, F.
1999
Comparison of (S)-mephenytoin and proguanil oxidation in vitro: contribution of several CYP isoforms.
Coller, J.
;
Somogyi, A.
;
Bochner, F.
2007
CYP2B6 CYP2D6 and CYP3A4 catalyze the primary oxidative metabolism of perhexiline enantiomers by human liver microsomes
Davies, B.
;
Coller, J.
;
Somogyi, A.
;
Milne, R.
;
Sallustio, B.
2015
Pharmacogenetics of opioid response
Somogyi, A.
;
Coller, J.
;
Barratt, D.
Discover
Author
16
Somogyi, A.
7
Sallustio, B.
4
Barratt, D.
4
Bochner, F.
4
Davies, B.
4
James, H.
3
Gillis, D.
3
Milne, R.
3
Morris, R.
3
Murdter, T.
.
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Subject
11
Male
10
Female
8
Cytochrome P-450 Enzyme System
8
Genotype
7
Adult
6
Aged
6
Microsomes, Liver
6
Middle Aged
5
Cytochrome P-450 CYP2D6
5
Oxidation-Reduction
.
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Date issued
3
2010 - 2018
13
2000 - 2009
4
1997 - 1999