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Issue Date
Title
Author(s)
2008
Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexiline
Davies, B.
;
Herbert, M.
;
Coller, J.
;
Somogyi, A.
;
Milne, R.
;
Sallustio, B.
2007
Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemia
Inglis, S.
;
Herbert, M.
;
Davies, B.
;
Coller, J.
;
James, H.
;
Horowitz, J.
;
Morris, R.
;
Milne, R.
;
Somogyi, A.
;
Sallustio, B.
2006
Enantioselective assay for the determination of perhexiline enantiomers in human plasma by liquid chromatography
Davies, B.
;
Herbert, M.
;
Culbert, J.
;
Pyke, S.
;
Coller, J.
;
Somogyi, A.
;
Milne, R.
;
Sallustio, B.
2006
Determination of the 4-monohydroxy metabolites of perhexiline in human plasma, urine and liver microsomes by liquid chromatography
Davies, B.
;
Herbert, M.
;
Coller, J.
;
Somogyi, A.
;
Milne, R.
;
Sallustio, B.
2007
CYP2B6 CYP2D6 and CYP3A4 catalyze the primary oxidative metabolism of perhexiline enantiomers by human liver microsomes
Davies, B.
;
Coller, J.
;
Somogyi, A.
;
Milne, R.
;
Sallustio, B.
Discover
Author
5
Sallustio, B.
4
Herbert, M.
1
Culbert, J.
1
Horowitz, J.
1
Inglis, S.
1
James, H.
1
Morris, R.
1
Pyke, S.
Subject
3
Humans
3
Perhexiline
3
Stereoisomerism
2
Cardiovascular Agents
2
Cytochrome P-450 CYP2D6
2
HPLC
2
Metabolic Clearance Rate
2
perhexiline
2
Polymorphism, Genetic
1
Aged
.
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Date issued
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2008
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2007
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2006