Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/17144
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Type: Journal article
Title: Expression of the immediate early gene, c-fos, in mouse brain after acute global system for mobile communication microwave exposure
Author: Finnie, J.
Citation: Pathology, 2005; 37(3):231-233
Publisher: Taylor & Francis
Issue Date: 2005
ISSN: 0031-3025
1465-3931
Abstract: AIMS:To study the effect of acute exposure to global system for mobile communication radiofrequency fields on immediate early gene, c-fos, expression in the brain. METHODS:Using a purpose-designed exposure system at 900 MHz, mice were given a single, far-field, whole body exposure for 60 minutes at a specific absorption rate of 4 W/kg. Control mice were sham-exposed or freely mobile in a cage without further restraint. c-fos protein expression was detected immunohistochemically in perfusion-fixed brains. RESULTS:Activation of c-fos in exposed and sham-exposed brains was comparable, but was greatly increased compared with freely moving controls. CONCLUSION:These results suggest that the majority of the acute genomic response detected by c-fos expression was due to immobilisation rather than irradiation.
Keywords: Brain; Animals; Mice; Restraint, Physical; Stress, Psychological; Genes, fos; Microwaves; Cell Phone
RMID: 0020050598
DOI: 10.1080/00313020500098942
Appears in Collections:Pathology publications

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