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|Title:||Expression of the immediate early gene, c-fos, in mouse brain after acute global system for mobile communication microwave exposure|
|Citation:||Pathology, 2005; 37(3):231-233|
|Publisher:||Taylor & Francis|
|Abstract:||AIMS:To study the effect of acute exposure to global system for mobile communication radiofrequency fields on immediate early gene, c-fos, expression in the brain. METHODS:Using a purpose-designed exposure system at 900 MHz, mice were given a single, far-field, whole body exposure for 60 minutes at a specific absorption rate of 4 W/kg. Control mice were sham-exposed or freely mobile in a cage without further restraint. c-fos protein expression was detected immunohistochemically in perfusion-fixed brains. RESULTS:Activation of c-fos in exposed and sham-exposed brains was comparable, but was greatly increased compared with freely moving controls. CONCLUSION:These results suggest that the majority of the acute genomic response detected by c-fos expression was due to immobilisation rather than irradiation.|
|Keywords:||Brain; Animals; Mice; Restraint, Physical; Stress, Psychological; Genes, fos; Microwaves; Cell Phone|
|Appears in Collections:||Pathology publications|
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