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https://hdl.handle.net/2440/23105
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dc.contributor.author | Finnie, J. | - |
dc.contributor.author | Cai, Z. | - |
dc.contributor.author | Blumbergs, P. | - |
dc.contributor.author | Manavis, J. | - |
dc.contributor.author | Kuchel, T. | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | Pathology, 2006; 38(4):333-335 | - |
dc.identifier.issn | 0031-3025 | - |
dc.identifier.issn | 1465-3931 | - |
dc.identifier.uri | http://hdl.handle.net/2440/23105 | - |
dc.description.abstract | <h4>Aims</h4>To study immediate early gene, c-fos, expression as a marker of neural stress after whole of gestation exposure of the fetal mouse brain to mobile telephone-type radiofrequency fields.<h4>Methods</h4>Using a purpose-designed exposure system at 900 MHz, pregnant mice were given a single, far-field, whole body exposure at a specific absorption rate of 4 W/kg for 60 min/day from day 1 to day 19 of gestation. Pregnant control mice were sham-exposed or freely mobile in a cage without further restraint. Immediately prior to parturition on gestational day 19, fetal heads were collected, fixed in 4% paraformaldehyde and paraffin embedded. Any stress response in the brain was detected by c-fos immunohistochemistry in the cerebral cortex, basal ganglia, thalamus, hippocampus, midbrain, cerebellum and medulla.<h4>Results</h4>c-fos expression was of limited, but consistent, neuroanatomical distribution and there was no difference in immunoreactivity between exposed and control brains.<h4>Conclusion</h4>In this animal model, no stress response was detected in the fetal brain using c-fos immunohistochemistry after whole of gestation exposure to mobile telephony. | - |
dc.language.iso | en | - |
dc.publisher | Taylor & Francis | - |
dc.source.uri | http://dx.doi.org/10.1080/00313020600820864 | - |
dc.subject | Brain | - |
dc.subject | Animals | - |
dc.subject | Mice, Inbred BALB C | - |
dc.subject | Mice | - |
dc.subject | Proto-Oncogene Proteins c-fos | - |
dc.subject | Immunohistochemistry | - |
dc.subject | Gene Expression Regulation, Developmental | - |
dc.subject | Pregnancy | - |
dc.subject | Genes, fos | - |
dc.subject | Microwaves | - |
dc.subject | Female | - |
dc.subject | Stress, Physiological | - |
dc.subject | Cell Phone | - |
dc.title | Expression of the immediate early gene, c-fos, in fetal brain after whole of gestation exposure of pregnant mice to global system for mobile communication microwaves | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1080/00313020600820864 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Finnie, J. [0000-0003-2277-1693] | - |
Appears in Collections: | Aurora harvest 6 Pathology publications |
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