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PreviewIssue DateTitleAuthor(s)
2017HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactionsZheng, J.; Chang, M.; Stites, R.; Wang, Y.; Bruning, J.; Pascal, B.; Novick, S.; Garcia-Ordonez, R.; Stayrook, K.; Chalmers, M.; Dodge, J.; Griffin, P.
2018Cytochrome P450 CYP199A4 from Rhodopseudomonas palustris catalyses heteroatom dealkylations, sulfoxidation and amide and cyclic hemiacetal formationColeman, T.; Wong, S.; Podgorski, M.; Bruning, J.; De Voss, J.; Bell, S.
2015Structural mechanism for signal transduction in RXR nuclear receptor heterodimersKojetin, D.; Matta-Camacho, E.; Hughes, T.; Srinivasan, S.; Nwachukwu, J.; Cavett, V.; Nowak, J.; Chalmers, M.; Marciano, D.; Kamenecka, T.; Shulman, A.; Rance, M.; Griffin, P.; Bruning, J.; Nettles, K.
2016SR2067 reveals a unique kinetic and structural signature for PPARγ partial agonismVan Marrewijk, L.; Polyak, S.; Hijnen, M.; Kuruvilla, D.; Chang, M.; Shin, Y.; Kamenecka, T.; Griffin, P.; Bruning, J.
2015Review of the structural and dynamic mechanisms of PPAR γ partial agonismKroker, A.; Bruning, J.
2013Rare variants in single-minded 1 (SIM1) are associated with severe obesityRamachandrappa, S.; Raimondo, A.; Cali, A.; Keogh, J.; Henning, E.; Saeed, S.; Thompson, A.; Garg, S.; Bochukova, E.; Brage, S.; Trowse, V.; Wheeler, E.; Sullivan, A.; Dattani, M.; Clayton, P.; Datta, V.; Bruning, J.; Wareham, N.; O'Rahilly, S.; Peet, D.; et al.
2012Structure of the apo form of Bacillus Stearothermophilus PhosphofructokinaseMosser, R.; Reddy, M.; Bruning, J.; Sacchettini, J.; Reinhart, G.
2015Pharmacological repression of PPARγ promotes osteogenesisMarciano, D.; Kuruvilla, D.; Boregowda, S.; Asteian, A.; Hughes, T.; Garcia-Ordonez, R.; Corzo, C.; Khan, T.; Novick, S.; Park, H.; Kojetin, D.; Phinney, D.; Bruning, J.; Kamenecka, T.; Griffin, P.
2013Redefining the role of the quaternary shift in bacillus stearothermophilus phosphofructokinaseMosser, R.; Reddy, M.; Bruning, J.; Sacchettini, J.; Reinhart, G.
2015p21 exploits residue Tyr151 as a tether for high-affinity PCNA bindingKroker, A.; Bruning, J.