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PreviewIssue DateTitleAuthor(s)
2010Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1Jarman, K.; Moretti, P.; Zebol, J.; Pitson, S.
2010The Sphingosine Kinase 1 Inhibitor 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole Induces Proteasomal Degradation of Sphingosine Kinase 1 in Mammalian CellsTonelli, F.; Loveridge, C.; Leclercq, T.; Lim, K.; Long, J.; Berdyshev, E.; Tate, R.; Natarajan, V.; Pitson, S.; Pyne, N.; Pyne, S.
2010Inhibitors of the sphingosine kinase pathway as potential therapeuticsPitman, M.; Pitson, S.
2010FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cellsTonelli, F.; Lim, K.; Loveridge, C.; Long, J.; Pitson, S.; Tigyi, G.; Bittman, R.; Pyne, S.; Pyne, N.
2010A proinflammatory role for proteolytically cleaved annexin A1 in neutrophil transendothelial migrationWilliams, S.; Milne, I.; Bagley, C.; Gamble, J.; Vadas, M.; Pitson, S.; Khew-Goodall, Y.
2010Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphateSiow, D.; Anderson, C.; Berdyshev, E.; Skobeleva, A.; Pitson, S.; Wattenberg, B.
2010Isoflurane protects human kidney proximal tubule cells against necrosis via sphingosine kinase and sphingosine-1-phosphate generationKim, M.; Kim, M.; Park, S.; Pitson, S.; Lee, H.
2010Isoflurane via TGF-β1 release increases caveolae formation and organizes sphingosine kinase signaling in renal proximal tubulesSong, J.; Kim, M.; Park, S.; Chen, S.; Pitson, S.; Lee, H.
2010Tumor necrosis factor-induced neutrophil adhesion occurs via sphingosine kinase-1-dependent activation of endothelial α₅β₁ integrinSun, W.; Pitson, S.; Bonder, C.
2010Sphingosine and FTY720 directly bind pro-survival 14-3-3 proteins to regulate their functionWoodcock, J.; Ma, Y.; Coolen, C.; Pham, D.; Jones, C.; Lopez, A.; Pitson, S.