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Type: Book chapter
Title: The 25-Hydroxyvitamin D 24-Hydroxylase
Author: Omdahl, John L.
May, B.
Citation: Vitamin D / D. Feldman, F. H. Glorieux, J. W. Pike(eds.), pp.69-85
Publisher: Academic Press
Issue Date: 1997
ISBN: 0122526856
School/Discipline: School of Molecular and Biomedical Science : Biochemistry
Abstract: This chapter reviews the role of 25-hydroxyvitamin D 24-hydroxylase in vitamin D metabolism. The 24-hydroxylase enzyme is a widely distributed component of the vitamin D pathway. It is regulated by a spectrum of hormones and functions to synthesise 24-hydroxylated metabolites, with preferential action in promoting bone mineralization and possibly other undisclosed cellular functions that may become evident through the use of gene knockout models. It also plays a central role in directing the metabolic turnover of several 25-hydroxylated vitamin D metabolites.
Appears in Collections:Biochemistry publications

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