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|Title:||The 25-Hydroxyvitamin D 24-Hydroxylase|
|Author:||Omdahl, John L.|
|Citation:||Vitamin D / D. Feldman, F. H. Glorieux, J. W. Pike(eds.), pp.69-85|
|School/Discipline:||School of Molecular and Biomedical Science : Biochemistry|
|Abstract:||This chapter reviews the role of 25-hydroxyvitamin D 24-hydroxylase in vitamin D metabolism. The 24-hydroxylase enzyme is a widely distributed component of the vitamin D pathway. It is regulated by a spectrum of hormones and functions to synthesise 24-hydroxylated metabolites, with preferential action in promoting bone mineralization and possibly other undisclosed cellular functions that may become evident through the use of gene knockout models. It also plays a central role in directing the metabolic turnover of several 25-hydroxylated vitamin D metabolites.|
|Appears in Collections:||Biochemistry publications|
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