Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/32800
Type: Conference item
Title: Ultrasound induced heating in fetal and neonatal brains is unaffected by altered blood flow
Author: Barnett, S.
Duggan, P.
Horder, M.
Vella, G.
Citation: Ultrasound in Medicine and Biology, 2000, vol.26, iss.SUPPL. 2, pp.PHO35-PHO35
Issue Date: 2000
ISSN: 0301-5629
Conference Name: Ultrasound in Medicine and Biology
Abstract: This paper reports effects of altered cerebral perfusion on ultrasound heating by a simulated pulsed Doppler beam in brains in two perinatal animal models. A 3.5 MHz transducer produced a -6 dB focal beamwidth of 0.26 cm in the brain. The animals were anaesthetized and the ultrasound beam was held stationary during exposure to Ispta intensities 2.8 (fetal guinea-pig in utero) and 1.4 W/cm 2 (neonatal pig). Each exposure was repeated after death. Blood flow in neonatal pigs was increased by induced hypercarbia/hypoxia. The mean maximum temperature increase after 90 s was 4.6 and 1.5 °C for third trimester fetuses and neonatal pigs, respectively. There was no difference between dead (non-perfused) and live (perfused) animals. Increasing blood flow by 200% above normal did not alter brain temperature in neonatal pigs. This supports theory that for clinically relevant narrow beams the extent of ultrasound-induced heating in brain tissue is not significantly altered by vascular perfusion.
Appears in Collections:Aurora harvest
Obstetrics and Gynaecology publications

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