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https://hdl.handle.net/2440/34469
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Type: | Journal article |
Title: | A diastereoselective synthesis of the tetrahydropyridazinone core of 2-oxo-1,6-diazobicyclo[4.3.0]nonane-9-carboxylate-based peptidomimetics starting from (S)-phenylalanine |
Author: | Gardiner, J. Abell, A. |
Citation: | Tetrahedron Letters: the international journal for the rapid publication of all preliminary communications in organic chemistry, 2003; 44(22):4227-4230 |
Publisher: | Pergamon-Elsevier Science Ltd |
Issue Date: | 2003 |
ISSN: | 0040-4039 |
Statement of Responsibility: | James Gardiner and Andrew D. Abell |
Abstract: | A diastereoseletvive synthesis of a peptidic tetrahydropyridazinone 10 from (S)-phenylalanine is reported. This derivative was then converted to the bicyclic peptidomimetic 11, an important class of β-strand mimetic. © 2003 Elsevier Science Ltd. All rights reserved. |
DOI: | 10.1016/S0040-4039(03)00882-7 |
Published version: | http://dx.doi.org/10.1016/s0040-4039(03)00882-7 |
Appears in Collections: | Aurora harvest 6 Chemistry publications |
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