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https://hdl.handle.net/2440/34854
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Type: | Journal article |
Title: | Synthesis of Trisubstituted Imidazoles by Palladium-Catalyzed Cyclization of O-Pentafluorobenzoylamidoximes: Application to Amino Acid Mimetics with a C-Terminal Imidazole |
Author: | Zaman, S. Mitsuru, K. Abell, A. |
Citation: | Organic Letters, 2005; 7(4):609-611 |
Publisher: | Amer Chemical Soc |
Issue Date: | 2005 |
ISSN: | 1523-7060 1523-7052 |
Statement of Responsibility: | Shazia Zaman, Kitamura Mitsuru, and Andrew D. Abell |
Abstract: | 1-Benzyl-4-methylimidazoles with a range of substituents at the 2-position are prepared from O-pentafluorobenzoylamidoximes on treatment with catalytic amounts of Pd(PPh₃)₄ and triethylamine. The sequence provides access to optically active amino acid mimetics with a C-terminal imidazole. |
Keywords: | Palladium Oximes Imidazoles Amino Acids Cyclization Catalysis Models, Molecular |
Description: | Copyright © 2005 American Chemical Society |
DOI: | 10.1021/ol047628p |
Published version: | http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2005/7/i04/abs/ol047628p.html |
Appears in Collections: | Aurora harvest Chemistry publications |
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