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Type: Journal article
Title: The epidemiology of lip cancer: a review of global incidence and aetiology
Author: Moore, S.
Johnson, N.
Pierce, A.
Wilson, D.
Citation: Oral Diseases, 1999; 5(3):185-195
Publisher: Wiley
Issue Date: 1999
ISSN: 1354-523X
Abstract: Lip cancer (140 ICD-9) is a form of oral cancer that has a distinctive global epidemiology. This review summarises global incidence rates for male and female lip cancer with the aid of cancer atlases. High male lip cancer rates are reported for regions of North America (12.7 per 100 000 per annum), Europe (12.0 per 100 000 per annum) and Oceania (13.5 per 100 000 per annum), while it is virtually unknown in parts of Asia. Factors commonly cited as important in the aetiology of lip cancer include solar radiation, tobacco smoking and viruses. An attempt is made to summarise the evidence for factors that may be important in lip carcinogenesis. While incidence rates are generally stable or falling among males worldwide, they are rising in many female populations. The aetiology of the disease is far from established and much information regarding its pathogenesis is based on anecdotal rather than case-controlled epidemiological evidence. The epidemiology of lip cancer supports the proposal that the lip should be considered as a distinct cancer site, rather than being included with other forms of intraoral cancer.
Keywords: Humans
Lip Neoplasms
Occupational Diseases
Genetic Predisposition to Disease
Sex Factors
Topography, Medical
North America
South America
Pacific Islands
DOI: 10.1111/j.1601-0825.1999.tb00300.x
Appears in Collections:Aurora harvest 6
Dentistry publications

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