Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/43119
Citations
Scopus Web of Science® Altmetric
?
?
Full metadata record
DC FieldValueLanguage
dc.contributor.authorHutchinson, A.en
dc.contributor.authorMathias, J.en
dc.date.issued2007en
dc.identifier.citationJournal of Neurology Neurosurgery and Psychiatry, 2007; 78(1):917-928en
dc.identifier.issn0022-3050en
dc.identifier.issn1468-330Xen
dc.identifier.urihttp://hdl.handle.net/2440/43119-
dc.descriptionCopyright © 2007 by the BMJ Publishing Group Ltd.en
dc.description.abstractWe sought to identify the cognitive tests that best discriminate between Alzheimer’s disease (AD) and frontotemporal dementia (FTD). A comprehensive search of all studies examining the cognitive performance of persons diagnosed with AD and FTD, published between 1980 and 2006, was conducted. Ninety-four studies were identified, comprising 2936 AD participants and 1748 FTD participants. Weighted Cohen’s d effect sizes, percentage overlap statistics, confidence intervals and fail-safe Ns were calculated for each cognitive test that was used by two or more studies. The most discriminating cognitive tests were measures of orientation, memory, language, visuomotor function and general cognitive ability. Although there were large and significant differences between groups on these measures, there was substantial overlap in the scores of the AD and FTD groups. Age, education, years since diagnosis and diagnostic criteria did not significantly contribute to the group differences. Given the large overlap in the test performance of persons diagnosed with AD and FTD, cognitive tests should be used cautiously and in conjunction with a medical history, behavioural observations, imaging and information from relatives when making differential diagnoses.en
dc.description.statementofresponsibilityA D Hutchinson, J L Mathiasen
dc.language.isoenen
dc.publisherBritish Med Journal Publ Groupen
dc.subjectHumans; Dementia; Alzheimer Disease; Diagnosis, Differential; Neuropsychological Testsen
dc.titleNeuropsychological deficits in frontotemporal dementia and Alzheimer's disease: a meta-analytic reviewen
dc.typeJournal articleen
dc.identifier.rmid0020070266en
dc.identifier.doi10.1136/jnnp.2006.100669en
dc.identifier.pubid49179-
pubs.library.collectionPsychology publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidHutchinson, A. [0000-0003-3983-8321]en
dc.identifier.orcidMathias, J. [0000-0001-8957-8594]en
Appears in Collections:Psychology publications

Files in This Item:
File Description SizeFormat 
hdl_43119.pdf270.85 kBPublisher's PDF View/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.