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https://hdl.handle.net/2440/43997
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Type: | Journal article |
Title: | Forensic issues in Down sydrome fatalities |
Author: | Byard, R. |
Citation: | Journal of Clinical Forensic and Legal Medicine: an international journal of forensic and legal medicine, 2007; 14(8):475-481 |
Publisher: | Churchill Livingstone |
Issue Date: | 2007 |
ISSN: | 1752-928X 1878-7487 |
Statement of Responsibility: | Roger W. Byard |
Abstract: | Down syndrome, or trisomy 21, is the most common chromosomal abnormality associated with intellectual impairment. Premature death is a feature of the syndrome due to a wide variety of conditions including congenital heart disease, impaired immune responses resulting in respiratory infections, acute leukaemia, upper airway narrowing, pulmonary hypertension, Alzheimer disease and atlantoaxial instability. Cases of Down syndrome not uncommonly present for medicolegal autopsy, as the non-specificity of symptoms and signs often precludes accurate antemortem establishment of a cause of death. Manifestations of Down syndrome are reviewed with an analysis of possible mechanisms of death and findings at autopsy. |
Keywords: | Atlanto-Axial Joint Brain Humans Leukemia Joint Instability Gastrointestinal Diseases Respiratory Insufficiency Central Nervous System Diseases Down Syndrome Heart Defects, Congenital Vascular Diseases Abnormalities, Multiple Diabetes Mellitus Immune System Diseases Asphyxia Death, Sudden Forensic Pathology Infections |
Description: | Copyright © 2007 Elsevier Ltd and FFLM All rights reserved. |
Provenance: | Former title: Journal of Clinical Forensic Medicine |
DOI: | 10.1016/j.jflm.2007.01.001 |
Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/711392/description#description |
Published version: | http://dx.doi.org/10.1016/j.jflm.2007.01.001 |
Appears in Collections: | Aurora harvest Pathology publications |
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