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https://hdl.handle.net/2440/44350
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dc.contributor.author | Nguyen, Q. | - |
dc.contributor.author | Lam, S. | - |
dc.contributor.author | Ching, K. | - |
dc.contributor.author | Chapman, M. | - |
dc.contributor.author | Fraser, R. | - |
dc.contributor.author | Holloway, R. | - |
dc.date.issued | 2007 | - |
dc.identifier.citation | Intensive Care Medicine, 2007; 33(10):1740-1745 | - |
dc.identifier.issn | 0342-4642 | - |
dc.identifier.issn | 1432-1238 | - |
dc.identifier.uri | http://hdl.handle.net/2440/44350 | - |
dc.description | © Springer The original publication can be found at www.springerlink.com | - |
dc.description.abstract | <h4>Objective</h4>To examine the occurrence of feed intolerance in critically ill patients with previously diagnosed type II diabetes mellitus (DM) who received prolonged gastric feeding.<h4>Design and setting</h4>Retrospective study in a level 3 mixed ICU.<h4>Patients</h4>All mechanically ventilated, enterally fed patients (n = 649), with (n = 118) and without type II DM (n = 531) admitted between January 2003 and July 2005.<h4>Interventions</h4>Patients with at least 72 h of gastric feeding were identified by review of case notes and ICU charts. The proportion that developed feed intolerance was determined. All patient received insulin therapy.<h4>Results</h4>The proportion of patients requiring gastric feeding for at least 72 h was similar between patients with and without DM (42%, 50/118, vs. 42%, 222/531). Data from patients with DM were also compared with a group of 50 patients matched for age, sex and APACHE II score, selected from the total non-diabetic group. The occurrence of feed intolerance (DM 52% vs. matched non-DM 50% vs. unselected non-diabetic 58%) and the time taken to develop feed intolerance (DM 62.6 +/- 43.8 h vs. matched non-DM 45.3 +/- 54.6 vs. unselected non-diabetic 50.6 +/- 59.5) were similar amongst the three groups. Feed intolerance was associated with a greater use of morphine/midazolam and vasopressor support, a lower feeding rate and a longer ICU length of stay.<h4>Conclusions</h4>In critically ill patients who require prolonged enteral nutrition, a prior history of DM type II does not appear to be a further risk factor for feed intolerance. | - |
dc.description.statementofresponsibility | N. Q. Nguyen, S. W. Lam, K. Ching, M. Chapman, R. J. Fraser and R. H. Holloway | - |
dc.language.iso | en | - |
dc.publisher | Springer | - |
dc.source.uri | http://www.springerlink.com/content/fh67655423941ln7/ | - |
dc.subject | Diabetes mellitus | - |
dc.subject | Gastric feed intolerance | - |
dc.subject | Critically ill | - |
dc.title | Gastric feed intolerance is not increased in critically ill patients with type II diabetes mellitus | - |
dc.type | Journal article | - |
dc.provenance | An erratum to this article can be found at http://dx.doi.org/10.1007/s00134-007-0777-x | - |
dc.identifier.doi | 10.1007/s00134-007-0712-1 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Nguyen, Q. [0000-0002-1270-5441] | - |
dc.identifier.orcid | Chapman, M. [0000-0003-0710-3283] | - |
Appears in Collections: | Aurora harvest 6 Medicine publications |
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