Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/47928
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dc.contributor.authorRuan, Y.en
dc.contributor.authorFoo, H.en
dc.contributor.authorWarren-Smith, S.en
dc.contributor.authorHoffmann, P.en
dc.contributor.authorMoore, R.en
dc.contributor.authorEbendorff-Heidepriem, H.en
dc.contributor.authorMonro, T.en
dc.date.issued2008en
dc.identifier.citationOptics Express, 2008; 16(22):18514-18523en
dc.identifier.issn1094-4087en
dc.identifier.issn1094-4087en
dc.identifier.urihttp://hdl.handle.net/2440/47928-
dc.description.abstractGlass microstructured optical fibers have been rendered biologically active for the first time via the immobilization of antibodies within the holes in the fiber cross-section. This has been done by introducing coating layers to the internal surfaces of soft glass fibers. The detection of proteins that bind to these antibodies has been demonstrated experimentally within this system via the use of fluorescence labeling. The approach combines the sensitivity resulting from the long interaction lengths of filled fibers with the selectivity provided by the use of antibodies.en
dc.description.statementofresponsibilityYinlan Ruan, Tze Cheung Foo, Stephen Warren-Smith, Peter Hoffmann, Roger C. Moore, Heike Ebendorff-Heidepriem, Tanya M. Monroen
dc.language.isoenen
dc.publisherOptical Soc Ameren
dc.rights© 2008 Optical Society of Americaen
dc.subjectGlass; Antibodies; Antigen-Antibody Complex; Solutions; Biosensing Techniques; Fluorescenceen
dc.titleAntibody immobilization within glass microstructured fibers: A route to sensitive and selective biosensorsen
dc.typeJournal articleen
dc.identifier.rmid0020082703en
dc.identifier.doi10.1364/OE.16.018514en
dc.identifier.pubid41976-
pubs.library.collectionIPAS publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidWarren-Smith, S. [0000-0002-2612-6344]en
Appears in Collections:Centre of Expertise in Photonics publications
IPAS publications

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