Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/50860
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Type: Journal article
Title: Comparative analysis of nucleotide sequences of Orientia tsutsugamushi in different epidemic areas of scrub typhus in Shandong, China
Author: Yang, L.
Zhao, Z.
Li, Z.
Wang, X.
Liu, Y.
Bi, P.
Citation: American Journal of Tropical Medicine and Hygiene, 2008; 78(6):968-972
Publisher: Amer Soc Trop Med & Hygiene
Issue Date: 2008
ISSN: 0002-9637
1476-1645
Statement of
Responsibility: 
Li-Ping Yang, Zhong-Tang Zhao, Zhong Li, Xian-Jun Wang, Yun-Xi Liu, and Peng Bi
Abstract: Scrub typhus, caused by Orientia tsutsugamushi, is a zoonosis that spreads rapidly in Shandong, China. To investigate the molecular characterization of O. tsutsugamushi in new and old epidemic areas in Shandong Province, we compared the genetic relationships of O. tsutsugamushi between Linyi and Tai'an districts, typical old and new epidemic areas in Shandong, respectively. O. tsutsugamushi was detected in blood from 12 of 16 patients in Linyi and in eschar from 3 of 4 patients in Tai'an; 17 of 128 rodents were found to be infected with O. tsutsugamushi in Linyi, and 4 of 68 rodents were found to be O. tsutsugamushi-positive in Tai'an. The results indicated less genetic variation in O. tsutsugamushi between the new and old epidemic areas, and the Sdu-1 type, similar to Japan Kawasaki, was the main genotype of O. tsutsugamushi in Shandong Province.
Keywords: Animals; Humans; Mice; Orientia tsutsugamushi; Scrub Typhus; Polymerase Chain Reaction; Disease Vectors; Phylogeny; China; Cricetinae
Description: Copyright © 2008 by The American Society of Tropical Medicine and Hygiene
RMID: 0020080855
DOI: 10.4269/ajtmh.2008.78.968
Appears in Collections:Public Health publications
Environment Institute publications

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