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https://hdl.handle.net/2440/52390
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Type: | Journal article |
Title: | A case of longitudinally extensive transverse myelitis (LETM): Neuromyelitis optica |
Author: | Mangat, P. Ravindran, J. Cleland, L. Limaye, V. |
Citation: | Clinical Rheumatology, 2008; 27(SUPPL 2):67-69 |
Publisher: | Springer-Verlag |
Issue Date: | 2008 |
ISSN: | 0770-3198 1434-9949 |
Statement of Responsibility: | Pamela Mangat, Janakan Ravindran, Les Cleland and Vidya Limaye |
Abstract: | Neuromyelitis optica (NMO), characterised by longitudinally extensive transverse myelitis (LETM), was previously thought to be a variant of multiple sclerosis. Transverse myelitis may be a manifestation of autoimmune connective tissue diseases and NMO is now recognised to be a humorally mediated autoimmune disease. We present a case of NMO associated with non-organ-specific autoantibodies and the absence of the characteristic NMO-IgG antibody. Our case provides an opportunity to review the diagnostic criteria of NMO and its distinction from other autoimmune and demyelinating conditions. We report successful treatment with plasmapheresis and rituximab in NMO-IgG-negative relapsing disease. |
Keywords: | Longitudinally extensive transverse myelitis (LETM) Neuromyelitis optica Rituximab |
Description: | The original publication can be found at www.springerlink.com |
DOI: | 10.1007/s10067-008-0936-7 |
Published version: | http://dx.doi.org/10.1007/s10067-008-0936-7 |
Appears in Collections: | Aurora harvest 5 Medicine publications |
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