Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/53334
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dc.contributor.authorMikocka-Walus, A.en
dc.contributor.authorTurnbull, D.en
dc.contributor.authorAndrews, J.en
dc.contributor.authorMoulding, N.en
dc.contributor.authorHoltmann, G.en
dc.date.issued2008en
dc.identifier.citationAlimentary Pharmacology & Therapeutics, 2008; 28(4):475-483en
dc.identifier.issn0269-2813en
dc.identifier.issn1365-2036en
dc.identifier.urihttp://hdl.handle.net/2440/53334-
dc.descriptionThe definitive version may be found at www.wiley.comen
dc.description.abstractBACKGROUND: Symptoms of functional gastrointestinal disorders (FGIDs) are common in patients with inflammatory bowel disease (IBD). Psychological comorbidities of anxiety and depression are also highly prevalent in IBD. AIM: To quantify the burden of FGIDs in a hospital-based cohort of patients with IBD and to determine whether there is any inter-relationship between the presence and number of FGIDs and patients' quality of life or psychological status. METHODS: A cross-sectional survey of 61 out-patients was performed. Data on psychological status, quality of life, disease activity and functional symptoms according to Rome III criteria were collected. RESULTS: Overall, 49 (80%) participants met Rome III criteria for a functional bowel disorder and 52% of participants met criteria for more than one FGID. Participants with no FGID had significantly better physical quality of life than those with more than two FGIDs (P = 0.025). However, there was no relationship among the number of FGIDs, mental quality of life, anxiety or depression. CONCLUSIONS: Functional gastrointestinal disorders are highly prevalent in out-patients with IBD. Somewhat unexpectedly, the presence of anxiety and/or depression did not appear to correlate with either the presence or the number of FGIDs.en
dc.description.statementofresponsibilityA. A. Mikocka-Walus, D. A. Turnbull, J. M. Andrews, N. T. Moulding & G. J. Holtmannen
dc.language.isoenen
dc.publisherBlackwell Publishing Ltden
dc.subjectHumans; Inflammatory Bowel Diseases; Questionnaires; Anxiety Disorders; Depressive Disorder; Quality of Life; Adult; Aged; Aged, 80 and over; Middle Aged; Female; Maleen
dc.titleThe effect of functional gastrointestinal disorders on psychological comorbidity and quality of life in patients with inflammatory bowel diseaseen
dc.typeJournal articleen
dc.identifier.rmid0020082349en
dc.identifier.doi10.1111/j.1365-2036.2008.03754.xen
dc.identifier.pubid42210-
pubs.library.collectionPsychology publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidMikocka-Walus, A. [0000-0003-4864-3956]en
dc.identifier.orcidTurnbull, D. [0000-0002-7116-7073]en
dc.identifier.orcidAndrews, J. [0000-0001-7960-2650]en
Appears in Collections:Psychology publications

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