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https://hdl.handle.net/2440/57437
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Type: | Journal article |
Title: | Lifestyle management improves quality of life and depression in overweight and obese women with polycystic ovary syndrome |
Author: | Thomson, R. Buckley, J. Lim, S. Noakes, M. Clifton, P. Norman, R. Brinkworth, G. |
Citation: | Fertility and Sterility, 2010; 94(5):1812-1819 |
Publisher: | Elsevier Science Inc |
Issue Date: | 2010 |
ISSN: | 0015-0282 1556-5653 |
Statement of Responsibility: | Rebecca L. Thomson, Jonathan D. Buckley, Siew S. Lim, Manny Noakes, Peter M. Clifton, Robert J. Norman and Grant D. Brinkworth |
Abstract: | Objective: To assess the impact of adding exercise to dietary restriction on depressive symptoms and health-related quality of life (HRQOL) in women with polycystic ovary syndrome (PCOS). Design: Analysis of depression and quality of life outcomes from a randomized, controlled prospective clinical intervention that evaluated the effects on a range of health outcomes in women with PCOS. Setting: Clinical research unit. Patient(s): One hundred four overweight/obese PCOS women (aged 29.3 ± 0.7 years; body mass index [BMI] 36.1 ± 0.5 kg/m2). Intervention(s): Randomized to one of three 20-week lifestyle programs: diet only, diet and aerobic exercise, or diet and combined aerobic-resistance exercise. Main Outcome Measure(s): Depression and PCOS-specific HRQOL. Result(s): Forty-nine women completed the intervention (diet only = 14, diet and aerobic exercise = 15, diet and combined aerobic-resistance exercise = 20). By week 20 all groups achieved weight loss and had improvements in depression and PCOS-specific HRQOL scores, except for body hair domain score. There was no difference between treatments for all outcomes. Conclusion(s): This study demonstrated that dietary restriction alone and combined with exercise had similar benefits for improving depression and HRQOL scores in overweight and obese women with PCOS. |
Keywords: | Weight loss exercise diet depression quality of life |
DOI: | 10.1016/j.fertnstert.2009.11.001 |
Published version: | http://dx.doi.org/10.1016/j.fertnstert.2009.11.001 |
Appears in Collections: | Aurora harvest 5 Obstetrics and Gynaecology publications |
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