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Type: Journal article
Title: Acute presentation of nasal-type natural killer/T-cell lymphoma of the orbit
Author: Qin, Wei
Yin, Zhengqin
Madge, Simon N.
Citation: European Journal of Ophthalmology, 2009; 19(4):679-682
Publisher: Wichtig Editore
Issue Date: 2009
ISSN: 1120-6721
School/Discipline: School of Medicine : Ophthalmology & Visual Sciences
Statement of
Wei Qin, Zhengqin Yin, and Simon N. Madge
Abstract: Purpose: An unusual case of nasal-type natural killer/T-cell lymphoma (NKTL) of the orbit is reported. Methods. The clinical history, computed tomography, magnetic resonance imaging, and biopsy specimen of a 29-year-old man with a right orbital lymphoma were evaluated. Results: The patient initially presented with conjunctival injection and had flu-like symptoms before developing right proptosis and reduced vision; imaging showed a diffuse infiltrative process throughout the orbit. Orbital biopsy revealed angiodestruction with prominent necrosis, and angiocentric lymphoma growth and lymphoma cells were positively stained for CD3, CD20, CD45RO, CD56, cytotoxic molecules (granzyme B and T-cell intracellular antigen-1), and Epstein-Barr virus. Conclusions: NKTL is rare and may present acutely; the imaging findings presented serve to highlight the radiologic features of the disease.
RMID: 0020093487
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Appears in Collections:Opthalmology & Visual Sciences publications

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