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Issue Date
Title
Author(s)
2010
Nilotinib-mediated inhibition of ABCB1 increases intracellular concentration of dasatinib in CML cells: implications for combination TKI therapy
Hiwase, D.
;
White, D.
;
Zrim, S.
;
Saunders, V.
;
Vaz de Melo, J.
;
Hughes, T.
2010
Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors
Hiwase, D.
;
White, D.
;
Powell, J.
;
Saunders, V.
;
Zrim, S.
;
Frede, A.
;
Guthridge, M.
;
Lopez, A.
;
D'Andrea, R.
;
To, L.
;
Vaz de Melo, J.
;
Kumar, S.
;
Hughes, T.
2007
Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity
White, D.
;
Saunders, V.
;
Dang, P.
;
Engler, J.
;
Venables, A.
;
Zrim, S.
;
Zannettino, A.
;
Lynch, K.
;
Manley, P.
;
Hughes, T.
2010
Functional activity of the OCT-1 protein is predictive of long-term outcome in patients with chronic-phase chronic myeloid leukemia treated with Imatinib
White, D.
;
Dang, P.
;
Engler, J.
;
Frede, A.
;
Osborn, M.
;
Saunders, V.
;
Manley, P.
;
Zrim, S.
;
Hughes, T.
2008
Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: therapeutic implications
Hiwase, D.
;
Saunders, V.
;
Hewett, D.
;
Frede, A.
;
Zrim, S.
;
Dang, P.
;
Eadie, L.
;
To, L.
;
Vaz de Melo, J.
;
Kumar, S.
;
Hughes, T.
;
White, D.
Discover
Author
3
Dang, P.
3
Frede, A.
3
Hiwase, D.
3
Vaz de Melo, J.
2
Engler, J.
2
Kumar, S.
2
Manley, P.
2
To, L.
1
D'Andrea, R.
1
Eadie, L.
.
next >
Subject
4
Humans
4
Pyrimidines
3
Benzamides
3
Imatinib Mesylate
3
Leukemia, Myelogenous, Chronic, B...
3
Organic Cation Transporter 1
3
Piperazines
2
Antineoplastic Agents
2
ATP Binding Cassette Transporter,...
2
ATP Binding Cassette Transporter,...
.
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Date issued
3
2010
1
2008
1
2007