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Results 1-10 of 11 (Search time: 0.002 seconds).
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PreviewIssue DateTitleAuthor(s)
2019OBI-3424, a novel AKR1c3-activated prodrug, exhibits potent efficacy against preclinical models of T-ALLEvans, K.; Duan, J.X.; Pritchard, T.; Jones, C.D.; McDermott, L.; Gu, Z.; Toscan, C.E.; El-Zein, N.; Mayoh, C.; Erickson, S.W.; Guo, Y.; Meng, F.; Jung, D.; Rathi, K.S.; Roberts, K.G.; Mullighan, C.G.; Shia, C.S.; Pearce, T.; Teicher, B.A.; Smith, M.A.; et al.
2019International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine gliomaTsoli, M.; Shen, H.; Mayoh, C.; Franshaw, L.; Ehteda, A.; Upton, D.; Carvalho, D.; Vinci, M.; Meel, M.H.; van Vuurden, D.; Plessier, A.; Castel, D.; Drissi, R.; Farrell, M.; Cryan, J.; Crimmins, D.; Caird, J.; Pears, J.; Francis, S.; Ludlow, L.E.A.; et al.
2019Disruptive variants of CSDE1 associate with autism and interfere with neuronal development and synaptic transmissionGuo, H.; Li, Y.; Shen, L.; Wang, T.; Jia, X.; Liu, L.; Xu, T.; Ou, M.; Hoekzema, K.; Wu, H.; Gillentine, M.A.; Liu, C.; Ni, H.; Peng, P.; Zhao, R.; Zhang, Y.; Phornphutkul, C.; Stegmann, A.P.A.; Prada, C.E.; Hopkin, R.J.; et al.
2019Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancerWatt, M.J.; Clark, A.K.; Selth, L.A.; Haynes, V.R.; Lister, N.; Rebello, R.; Porter, L.H.; Niranjan, B.; Whitby, S.T.; Lo, J.; Huang, C.; Schittenhelm, R.B.; Anderson, K.E.; Furic, L.; Wijayaratne, P.R.; Matzaris, M.; Montgomery, M.K.; Papargiris, M.; Norden, S.; Febbraio, M.; et al.
2019A niche-dependent myeloid transcriptome signature defines dormant myeloma cellsKhoo, W.H.; Ledergor, G.; Weiner, A.; Roden, D.L.; Terry, R.L.; McDonald, M.M.; Chai, R.C.; De Veirman, K.; Owen, K.L.; Opperman, K.S.; Vandyke, K.; Clark, J.R.; Seckinger, A.; Kovacic, N.; Nguyen, A.; Mohanty, S.T.; Pettitt, J.A.; Xiao, Y.; Corr, A.P.; Seeliger, C.; et al.
2019Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunityZammit, N.W.; Siggs, O.M.; Gray, P.E.; Horikawa, K.; Langley, D.B.; Walters, S.N.; Daley, S.R.; Loetsch, C.; Warren, J.; Yap, J.Y.; Cultrone, D.; Russell, A.; Malle, E.K.; Villanueva, J.E.; Cowley, M.J.; Gayevskiy, V.; Dinger, M.E.; Brink, R.; Zahra, D.; Chaudhri, G.; et al.
2019Treatment of type 2 diabetes with the designer cytokine IC7FcFindeisen, M.; Allen, T.L.; Henstridge, D.C.; Kammoun, H.; Brandon, A.E.; Baggio, L.L.; Watt, K.I.; Pal, M.; Cron, L.; Estevez, E.; Yang, C.; Kowalski, G.M.; O'Reilly, L.; Egan, C.; Sun, E.; Thai, L.M.; Krippner, G.; Adams, T.E.; Lee, R.S.; Grötzinger, J.; et al.
2019Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemiaMoujalled, D.M.; Pomilio, G.; Ghiurau, C.; Ivey, A.; Salmon, J.; Rijal, S.; Macraild, S.; Zhang, L.; Teh, T.C.; Tiong, I.S.; Lan, P.; Chanrion, M.; Claperon, A.; Rocchetti, F.; Zichi, A.; Kraus-Berthier, L.; Wang, Y.; Halilovic, E.; Morris, E.; Colland, F.; et al.
2019TCF-1 limits the formation of Tc17 cells via repression of the MAF–RORγt axisMielke, L.A.; Liao, Y.; Clemens, E.B.; Firth, M.A.; Duckworth, B.; Huang, Q.; Almeida, F.F.; Chopin, M.; Koay, H.F.; Bell, C.A.; Hediyeh-Zadeh, S.; Park, S.L.; Raghu, D.; Choi, J.; Putoczki, T.L.; Hodgkin, P.D.; Franks, A.E.; Mackay, L.K.; Godfrey, D.I.; Davis, M.J.; et al.
2019PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemiaMcRae, H.M.; Garnham, A.L.; Hu, Y.; Witkowski, M.T.; Corbett, M.A.; Dixon, M.P.; May, R.E.; Sheikh, B.N.; Chiang, W.; Kueh, A.J.; Nguyen, T.A.; Man, K.; Gloury, R.; Aubrey, B.J.; Policheni, A.; Di Rago, L.; Alexander, W.S.; Gray, D.H.D.; Strasser, A.; Hawkins, E.D.; et al.