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https://hdl.handle.net/2440/60458
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dc.contributor.author | Ma, J. | - |
dc.contributor.author | Stevens, J. | - |
dc.contributor.author | Maddox, A. | - |
dc.contributor.author | Wishart, J. | - |
dc.contributor.author | Jones, K. | - |
dc.contributor.author | Clifton, P. | - |
dc.contributor.author | Horowitz, M. | - |
dc.contributor.author | Rayner, C. | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | Diabetes Care, 2009; 32(9):1600-1602 | - |
dc.identifier.issn | 0149-5992 | - |
dc.identifier.issn | 1935-5548 | - |
dc.identifier.uri | http://hdl.handle.net/2440/60458 | - |
dc.description.abstract | OBJECTIVE: We evaluated whether a whey preload could slow gastric emptying, stimulate incretin hormones, and attenuate postprandial glycemia in type 2 diabetes. RESEARCH DESIGN AND METHODS: Eight type 2 diabetic patients ingested 350 ml beef soup 30 min before a potato meal; 55 g whey was added to either the soup (whey preload) or potato (whey in meal) or no whey was given. RESULTS: Gastric emptying was slowest after the whey preload (P < 0.0005). The incremental area under the blood glucose curve was less after the whey preload and whey in meal than after no whey (P < 0.005). Plasma glucose-dependent insulinotropic polypeptide, insulin, and cholecystokinin concentrations were higher on both whey days than after no whey, whereas glucagon-like peptide 1 was greatest after the whey preload (P < 0.05). CONCLUSIONS: Whey protein consumed before a carbohydrate meal can stimulate insulin and incretin hormone secretion and slow gastric emptying, leading to marked reduction in postprandial glycemia in type 2 diabetes. | - |
dc.description.statementofresponsibility | Jing Ma, Julie E. Stevens, Kimberly Cukier, Anne F. Maddox, Judith M. Wishart, Karen L. Jones, Peter M. Clifton, Michael Horowitz, and Christopher K. Rayner | - |
dc.language.iso | en | - |
dc.publisher | Amer Diabetes Assoc | - |
dc.rights | © 2009 by the American Diabetes Association. | - |
dc.source.uri | http://dx.doi.org/10.2337/dc09-0723 | - |
dc.subject | Humans | - |
dc.subject | Diabetes Mellitus, Type 2 | - |
dc.subject | Gastrointestinal Hormones | - |
dc.subject | Cholecystokinin | - |
dc.subject | Insulin | - |
dc.subject | Blood Glucose | - |
dc.subject | Dietary Proteins | - |
dc.subject | Gastric Emptying | - |
dc.subject | Middle Aged | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.subject | Glucagon-Like Peptide 1 | - |
dc.title | Effects of a protein preload on gastric emptying, glycemia, and gut hormones after a carbohydrate meal in diet-controlled Type 2 diabetes | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.2337/dc09-0723 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Jones, K. [0000-0002-1155-5816] | - |
dc.identifier.orcid | Clifton, P. [0000-0002-6411-626X] | - |
dc.identifier.orcid | Horowitz, M. [0000-0002-0942-0306] | - |
dc.identifier.orcid | Rayner, C. [0000-0002-5527-256X] | - |
Appears in Collections: | Aurora harvest 5 Medicine publications |
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