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https://hdl.handle.net/2440/61224
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Type: | Journal article |
Title: | Using the Short Form-36 mental summary score as an indicator of depressive symptoms in patients with coronary heart disease |
Author: | Tavella, R. Air, T. Tucker, G. Adams, R. Beltrame, J. Schrader, G. |
Citation: | Quality of Life Research, 2010; 19(8):1105-1113 |
Publisher: | Kluwer Academic Publ |
Issue Date: | 2010 |
ISSN: | 0962-9343 1573-2649 |
Statement of Responsibility: | Rosanna Tavella, Tracy Air, Graeme Tucker, Robert Adams, John F. Beltrame and Geoffrey Schrader |
Abstract: | Background: Depression is common in patients with cardiac disease; however, the use of depression-specific health instruments is limited by their increased responder and analyst burden. The study aimed to define a threshold value on the Short Form-36 (SF-36) mental component summary score (MCS) that identified depressed cardiac patients as measured by the Centre for Epidemiologic Studies Depression Scale (CES-D). Methods: An optimal threshold was determined using receiver-operating characteristic (ROC) curves on SF-36 and CES-D data from a large cardiac cohort (N = 1,221). The performance of this threshold was evaluated in a further two cardiac populations. Results: In the index cohort, an SF-36 MCS score of ≤45 was revealed as an optimal threshold according to maximal Youden Index, with high sensitivity (77%, 95% CI = 74–80%) and specificity (73%, 95% CI = 69–77%). At this threshold, in a second sample of hospital cardiac patients, sensitivity was 93% (95% CI = 76–99%) and specificity was 64% (95% CI = 49–77%). In a final sample generated from a community population, specificity was 100% (95% CI = 85–100%) and sensitivity was 68% (95% CI = 61–74%) at the cut-off of 45. Conclusion: The SF-36 MCS may be a useful research tool to aid in the classification of cardiac patients according to the presence or absence of depressive symptoms. |
Keywords: | Coronary heart disease Short-Form 36 mental summary score Centre for Epidemiologic Studies Depression Scale Depression Optimal threshold |
Rights: | © Springer Science+Business Media B.V. 2010 |
DOI: | 10.1007/s11136-010-9671-z |
Published version: | http://dx.doi.org/10.1007/s11136-010-9671-z |
Appears in Collections: | Aurora harvest 5 Medicine publications |
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