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https://hdl.handle.net/2440/66125
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dc.contributor.author | Martens, T. | - |
dc.contributor.author | See, F. | - |
dc.contributor.author | Shuster, M. | - |
dc.contributor.author | Sondermeijer, H. | - |
dc.contributor.author | Hefti, M. | - |
dc.contributor.author | Zannettino, A. | - |
dc.contributor.author | Gronthos, S. | - |
dc.contributor.author | Seki, T. | - |
dc.contributor.author | Itescu, S. | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | Nature Reviews Cardiology, 2006; 3(Suppl 1):18-22 | - |
dc.identifier.issn | 1743-4297 | - |
dc.identifier.issn | 1743-4300 | - |
dc.identifier.uri | http://hdl.handle.net/2440/66125 | - |
dc.description.abstract | Mesenchymal lineage precursors can be reproducibly isolated from adult mammalian bone marrow and grown in culture. Immunoselection with monoclonal antibodies against STRO-1 and vascular-cell-adhesion molecule 1 (VCAM1/CD106) prior to expansion results in a 1,000-fold enrichment of mesenchymal precursors compared to standard isolation techniques. Intramyocardial injection of human STRO-1-selected precursors in an athymic rat model of acute myocardial infarction results in induction of vascular network formation and arteriogenesis coupled with global functional cardiac recovery. | - |
dc.description.statementofresponsibility | Timothy P Martens, Fiona See, Michael D Schuster, Hugo P Sondermeijer, Marco M Hefti, Andrew Zannettino, Stan Gronthos, Tetsunori Seki and Silviu Itescu | - |
dc.language.iso | en | - |
dc.publisher | Nature Publishing Group | - |
dc.rights | © 2006 Nature Publishing Group | - |
dc.source.uri | http://dx.doi.org/10.1038/ncpcardio0404 | - |
dc.subject | cardiac myogenesis | - |
dc.subject | cardiac neovascularization | - |
dc.subject | mesenchymal precursor cells | - |
dc.subject | STRO-1 | - |
dc.subject | VCAM1 | - |
dc.title | Mesenchymal lineage precursor cells induce vascular network formation in ischemic myocardium | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1038/ncpcardio0404 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Zannettino, A. [0000-0002-6646-6167] | - |
dc.identifier.orcid | Gronthos, S. [0000-0002-6225-3084] | - |
Appears in Collections: | Aurora harvest Medicine publications |
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