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https://hdl.handle.net/2440/66789
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Type: | Journal article |
Title: | Biomedical applications of X-ray absorption and vibrational spectroscopic microscopies in obtaining structural information from complex systems |
Author: | Aitken, J. Carter, E. Eastgate, H. Hackett, M. Harris, H. Levina, A. Lee, Y. Chen, C. Lai, B. Vogt, S. Lay, P. |
Citation: | Radiation Physics and Chemistry: the journal for radiation physics, radiation chemistry and radiation processing, 2010; 79(2):176-184 |
Publisher: | Pergamon-Elsevier Science Ltd |
Issue Date: | 2010 |
ISSN: | 0969-806X |
Statement of Responsibility: | Jade B. Aitken, Elizabeth A. Carter, Harold Eastgate, Mark J. Hackett, Hugh H. Harris, Aviva Levina, Yao-Chang Lee, Ching-Iue Chen, Barry Lai, Stefan Vogt, Peter A. Lay |
Abstract: | Protein crystallography and NMR spectroscopy took decades to emerge as routine techniques in structural biology. X-ray absorption spectroscopy now has reached a similar stage of maturity for obtaining complementary local structural information around metals in metalloproteins. However, the relatively recent emergence of X-ray and vibrational spectroscopic microprobes that build on these techniques has enabled the structural information obtained from the "mature" techniques on isolated biomolecules to be translated into in situ structural information from inhomogeneous complex systems, such as whole cells and tissues. © 2009 Elsevier Ltd. |
Keywords: | X-ray absorption spectroscopy X-ray microprobe FTIR microprobe Raman microprobes Cells Tissues |
Rights: | Copyright © 2009 Elsevier Ltd. Published by Elsevier B.V. All rights reserved. |
DOI: | 10.1016/j.radphyschem.2009.03.068 |
Published version: | http://dx.doi.org/10.1016/j.radphyschem.2009.03.068 |
Appears in Collections: | Aurora harvest Chemistry publications Environment Institute publications |
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