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dc.contributor.authorRowell, D.en
dc.contributor.authorLim, S.en
dc.contributor.authorGrutzner, F.en
dc.identifier.citationMethods in Molecular Biology - Volume 772 - Molecular Methods for Evolutionary Genetics, 2011 / Orgogozo, V., Rockman, M. (ed./s), pp.13-36en
dc.description.abstractThe revolution in molecular techniques over the last 30 years detracted from many traditional cytological techniques for examining basic biological problems. One of these casualties is the preparation of karyotypes and analysis of chromosomal structure, behaviour, and variation. Recent technology permitting the full sequencing of organisms has highlighted (but does not replace) the importance of understanding chromosomal constitution and karyotype structure, which underpin genome organisation. This chapter provides simple and straightforward protocols for the preparation of chromosome spreads from animals, and more advanced techniques for cell culture and chromosomal banding and hybridisation.en
dc.description.statementofresponsibilityDavid M. Rowell, Shu Ly Lim, and Frank Grutzneren
dc.relation.ispartofseriesMethods in Molecular Biology ; 772en
dc.rights© Springer Science+Business Media, LLC 2011en
dc.subjectChromosomes; Invertebrate genetics; Cytological techniques; Karyology; Cell culture; Fluorescence in situ hybridisationen
dc.titleChromosome Analysis in Invertebrates and Vertebratesen
dc.typeBook chapteren
dc.publisher.placeUnited Statesen
pubs.library.collectionGenetics publicationsen
dc.identifier.orcidGrutzner, F. [0000-0002-3088-7314]en
Appears in Collections:Genetics publications
Environment Institute Leaders publications

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