Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/71604
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Type: Book chapter
Title: Proteomic Characterization of Mesenchymal Stem Cell-Like Populations Derived from Various Tissue Types
Author: Mrozik, K.
Xiong, J.
Zilm, P.
Gronthos, S.
Bartold, P.
Citation: Stem cells and cancer stem cells: Therapeutic applications in disease and injury. Volume 3, 2012 / Hayat, M. (ed./s), pp.75-94
Publisher: Springer
Publisher Place: New York
Issue Date: 2012
ISBN: 9789400724143
Statement of
Responsibility: 
Krzysztof M. Mrozik, Jimin Xiong, Peter S. Zilm, Stan Gronthos and P. Mark Bartold
Abstract: The evolution of proteomics has led to its application in identifying biomarkers of biological processes and pathways including signal transduction and cell development. Proteomic technologies are increasingly utilized to define the molecular mechanisms controlling mesenchymal stem/stromal cell (MSC) self-renewal, multipotency and fate. Bone marrow derived MSCs are highly promising candidates in regenerative medicine based on their high proliferative capacity, multi-lineage differentiation potential and immunomodulatory properties. Recently, equivalent MSC-like populations have also been isolated from adipose, dental and various feto-maternal tissues. This chapter discusses the current technologies available for proteomic analysis and the studies performed on tissue-specific MSC-like populations to date.
Keywords: Adipose tissue; bone marrow; periodontal ligament; dental pulp; umbilical cord blood; Mesenchymal stem cells (MSCs)
Description: Stem Cells and Cancer Stem Cells; vol. 3
RMID: 0020118407
DOI: 10.1007/978-94-007-2415-0
Appears in Collections:Dentistry publications

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