Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/71898
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Type: Journal article
Title: Effects of space allocation and housing density on measures of wellbeing in laboratory mice: a review
Author: Whittaker, A.
Howarth, G.
Hickman, D.
Citation: Laboratory Animals, 2012; 46(1):3-13
Publisher: Royal Soc Medicine Press Ltd
Issue Date: 2012
ISSN: 0023-6772
1758-1117
Statement of
Responsibility: 
A.L. Whittaker, G.S. Howarth and D.L. Hickman
Abstract: In the majority of countries where there are legislative requirements pertaining to the use of animals in research, figures are quoted for minimum cage sizes or space allocation to be provided per animal. These figures are generally based on professional judgement and are in common usage. However, there is a growing trend and expectation that welfare science should inform regulatory decision-making. Given the importance of the potential welfare influences of cage size on the animals themselves, this paper presents the latest scientific knowledge on this topic in one of the most commonly used animals in research, the mouse. A comprehensive review of studies in laboratory mice was undertaken, examining the effects of space allocation per animal and animal density on established welfare indicators. To date, animal density studies have predominated, and the effects of space allocation per se are still relatively unclear. This information will guide those involved in facility management or legislative review, and provide a more solid foundation for further studies into the effects of routine husbandry practices on animal welfare.
Keywords: Animals; Mice; Spatial Behavior; Housing, Animal; Population Density; Sex Distribution; Animal Welfare; Social Environment
Rights: © Laboratory Animals Ltd.
RMID: 0020116734
DOI: 10.1258/la.2011.011049
Appears in Collections:Animal and Veterinary Sciences publications

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