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Type: Journal article
Title: Molecular Characterization of a Nonneuronal Human Unc18 Homolog
Author: Ziegler, S.
Mortrud, M.
Swartz, A.
Baker, E.
Sutherland, G.
Burmeister, M.
Mulligan, J.
Citation: Genomics, 1996; 37(1):19-23
Issue Date: 1996
ISSN: 0888-7543
Abstract: A cDNA clone encoding a human homolog of the Caenorhabditis elegans unc-18 gene was identified following random sequencing of clones from IL-2-activated human NK cells. This cDNA clone is related to the nonneuronal Munc-18b and so has been called Hunc-18b. The Hunc-18b transcripts were found in most human tissues, with the exception of brain and skeletal muscle, and in cells from all lymphoid lineages. The Hunc-18b gene was localized to human chromosome 19p13.2-p13.3, and the mouse homolog, Munc-18b, was mapped to the proximal region of mouse Chromosome 8.
Keywords: Chromosomes, Human, Pair 19; Animals; Humans; Mice; Vesicular Transport Proteins; Nerve Tissue Proteins; DNA, Complementary; In Situ Hybridization, Fluorescence; Chromosome Mapping; Cloning, Molecular; Amino Acid Sequence; Sequence Homology, Amino Acid; Molecular Sequence Data; Munc18 Proteins
RMID: 0030005631
DOI: 10.1006/geno.1996.0515
Appears in Collections:Paediatrics publications

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