Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/73099
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Type: Journal article
Title: The effect of orbital decompression surgery on refraction and intraocular pressure in patients with thyroid orbitopathy
Author: Norris, J.
Ross, J.
Kazim, M.
Selva-Nayagam, D.
Malhotra, R.
Citation: Eye, 2012; 26(4):535-543
Publisher: Nature Publishing Group
Issue Date: 2012
ISSN: 0950-222X
1476-5454
Statement of
Responsibility: 
JH Norris, JJ Ross, M Kazim, D Selva, and R Malhotra
Abstract: Purpose: To investigate the effect of orbital decompression surgery in thyroid orbitopathy (TO) on both refractive status and intraocular pressure (IOP). Patients and methods: A prospective, multicentre, consecutive audit of patients undergoing thyroid decompression surgery. Indications for surgery included cosmetically unacceptable proptosis or corneal exposure. Exclusion criteria included the following: previous orbital surgery, glaucoma, corneal disease, steroid use in the preceding 12 months, or an acute optic neuropathy. Automated refraction, keratometry, pachymetry, Hertel exophthalmometry, and IOP were recorded at 1 month pre- and 3 months postoperatively. IOP using the Tono-Pen (mean of three readings) was measured in the primary, upgaze, and downgaze positions. Results: Data were collected from 52 orbits of 33 patients (East Grinstead, New York, and Adelaide). There was no significant difference between pre- and postoperative data for sphere, cylinder, or central corneal thickness (CCT). The mean spherical equivalent was −0.43±1.49 D pre-operatively and −0.28±1.52 D postoperatively. The steepest meridian of corneal curvature was 93.1 degrees pre- and 94.2 degrees postoperatively, with no significant difference. Mean IOP significantly decreased when measuring by Goldmann applanation tonometry (GAT) (2.28 mm Hg, * P=0.001) and Tono-Pen (3.06 mm Hg, * P=<0.0001). IOP measured in upgaze was significantly greater than that in the primary position. Regression analysis between change in IOP and either Hertel exophthalmometry or the number of orbital walls decompressed was non-significant (*Student's t-test). Conclusion: Patients with TO undergoing orbital decompression had, on average, with-the-rule astigmatism not affected by orbital decompression surgery. IOP was significantly reduced by decompression surgery although no relationship between IOP and the degree of decompression was observed.
Keywords: thyroid; orbital decompression; refraction; intraocular pressure; pachymetry
Rights: © 2012 Macmillan Publishers Limited
RMID: 0020118373
DOI: 10.1038/eye.2011.362
Appears in Collections:Opthalmology & Visual Sciences publications

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