Adelaide Research & Scholarship
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https://hdl.handle.net/2440/7400
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| Type: | Journal article |
| Title: | Humoral immune responses of Solomon Islanders to the merozoite surface antigen 2 (MSA2,MSP2) of Plasmodium falciparum show pronounced skewing towards antibodies of the IgG3 subclass |
| Author: | Rzepczyk, C. Hale, K. Woodroffe, N. Bobogare, A. Csurhes, P. Ishii, A. Ferrante, A. |
| Citation: | Infection and Immunity, 1997; 65(3):1098-1100 |
| Publisher: | AMER SOC MICROBIOLOGY |
| Issue Date: | 1997 |
| ISSN: | 0019-9567 1098-5522 |
| Statement of Responsibility: | Christine M. Rzepczyk, Kate Hale, Nick Woodroffe, Albino Bobogare, Peter Csurhes, Akira Ishii, And Antonio Ferrante |
| Abstract: | The immunoglobulin G (IgG) subclass distribution of antibodies to merozoite surface antigen 2 of Plasmodium falciparum in Solomon Islanders showed marked skewing towards the IgG3 subclass. This was not observed with crude P. falciparum schizont antigen. IgG3 responses may be short-lived and require repeated restimulation for their maintenance. This may be provided by persistent infection (premunition) or new infections. |
| Keywords: | Animals Humans Plasmodium falciparum Immunoglobulin G Protozoan Proteins Antibodies, Protozoan Antigens, Protozoan Adolescent Adult Middle Aged |
| DOI: | 10.1128/iai.65.3.1098-1100.1997 |
| Published version: | http://dx.doi.org/10.1128/iai.65.3.1098-1100.1997 |
| Appears in Collections: | Aurora harvest 5 Paediatrics publications |
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