Adelaide Research & Scholarship
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https://hdl.handle.net/2440/75155
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| Type: | Journal article |
| Title: | A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides |
| Author: | Ma, M. Karas, J. White, J. Scanlon, D. Donnelly, P. |
| Citation: | Chemical Communications, 2009; 14(22):3237-3239 |
| Publisher: | Royal Soc Chemistry |
| Issue Date: | 2009 |
| ISSN: | 1359-7345 1364-548X |
| Statement of Responsibility: | Michelle T. Ma, John A. Karas, Jonathan M. White, Denis Scanlon and Paul S. Donnelly |
| Abstract: | A new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr3]- octreotate and [Lys3]-bombesin) and the conjugates radiolabelled with copper-64. |
| Keywords: | Animals Humans Copper Amines Carboxylic Acids Peptides Chelating Agents Cross-Linking Reagents Radiopharmaceuticals Ligands |
| Rights: | © The Royal Society of Chemistry 2009 |
| DOI: | 10.1039/B903426A |
| Published version: | http://dx.doi.org/10.1039/b903426a |
| Appears in Collections: | Aurora harvest Medical Sciences publications |
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