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https://hdl.handle.net/2440/80106
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Type: | Conference paper |
Title: | Antibody immobilization within glass microstructured fibers: a route to sensitive and selective biosensors |
Author: | Monro, T. Ruan, Y. Ebendorff-Heidepriem, H. Foo, H. Hoffmann, P. Moore, R. |
Citation: | 19th International Conference on Optical Fibre Sensors, 15–18 April 2008, Perth, Australia / D. Sampson, S. Collins, K. Oh, R. Yamauchi (eds.): 70046Q |
Publisher: | Society of Photo-Optical Instrumentation Engineers |
Issue Date: | 2008 |
Series/Report no.: | Proceedings of SPIE |
ISBN: | 9780819472045 |
ISSN: | 0277-786X |
Conference Name: | International Conference on Optical Fibre Sensors (19th : 2008 : Perth, W. Aust.) |
Editor: | Sampson, D. Collins, S. Oh, K. Yamauchi, R. |
Statement of Responsibility: | T.M. Monro, Y. Ruan, H. Ebendorff-Heidepriem, H. Foo, P. Hoffmann, R.C. Moore |
Abstract: | Glass microstructured optical fibers have been rendered biologically active for the first time active via the immobilization of antibodies within the holes in the fiber cross-section. This has been done by introducing coating layers to the internal surfaces of soft glass fibers. The detection of proteins that bind to these antibodies has been demonstrated experimentally within this system via the use of fluorescence labeling. The approach combines the sensitivity resulting from the long interaction lengths of filled fibers with the selectivity provided by the use of antibodies. |
Keywords: | Fiber fabrication & processing fluorescence sensing biosensing protein sensing. |
Rights: | Copyright © 2008, Society of Photo-Optical Instrumentation Engineers |
DOI: | 10.1117/12.801887 |
Published version: | http://dx.doi.org/10.1117/12.801887 |
Appears in Collections: | Aurora harvest 4 IPAS publications |
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