Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/80348
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Type: Journal article
Title: Diabetic gastroparesis: Recent insights into pathophysiology and implications for management
Author: Sebastian Thazhath, S.
Jones, K.
Horowitz, M.
Rayner, C.
Citation: Expert Review of Gastroenterology and Hepatology, 2013; 7(2):127-139
Publisher: Expert Reviews Ltd.
Issue Date: 2013
ISSN: 1747-4124
1747-4132
Statement of
Responsibility: 
Sony S Thazhath, Karen L Jones, Michael Horowitz and Christopher K Rayner
Abstract: Delayed gastric emptying affects a substantial proportion of patients with long-standing diabetes, and when associated with symptoms and/or disordered glycemic control, affects quality of life adversely. Important clinicopathological insights have recently been gained by the systematic analysis of gastric biopsies from patients with severe diabetic gastroparesis, which may stimulate the development of new therapies in the coming decade. Experience with prokinetic therapies and treatments, such as pyloric botulinum toxin injection and gastric electrical stimulation, has established that relief of symptoms does not correlate closely with acceleration of delayed gastric emptying, and that well-designed controlled trials are essential to determine the efficacy of emerging therapies.
Keywords: Humans
Gastroparesis
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Diabetes Complications
Antiemetics
Neuromuscular Agents
Botulinum Toxins
Magnetic Resonance Imaging
Prognosis
Complementary Therapies
Electric Stimulation Therapy
Nutritional Status
Gastrointestinal Motility
Gastric Emptying
Muscle Contraction
Neural Stem Cells
Pain Management
Rights: Copyright status unknown
DOI: 10.1586/egh.12.82
Published version: http://dx.doi.org/10.1586/egh.12.82
Appears in Collections:Aurora harvest
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