Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/80376
Citations
Scopus Web of Science® Altmetric
?
?
Type: Journal article
Title: Improving asthma during pregnancy with dietary antioxidants: the current evidence
Author: Grieger, J.
Wood, L.
Clifton, V.
Citation: Nutrients, 2013; 5(8):3212-3234
Publisher: MDPI
Issue Date: 2013
ISSN: 2072-6643
2072-6643
Statement of
Responsibility: 
Jessica A. Grieger, Lisa G. Wood and Vicki L. Clifton
Abstract: The complication of asthma during pregnancy is associated with a number of poor outcomes for the mother and fetus. This may be partially driven by increased oxidative stress induced by the combination of asthma and pregnancy. Asthma is a chronic inflammatory disease of the airways associated with systemic inflammation and oxidative stress, which contributes to worsening asthma symptoms. Pregnancy alone also intensifies oxidative stress through the systemic generation of excess reactive oxidative species (ROS). Antioxidants combat the damaging effects of ROS; yet antioxidant defenses are reduced in asthma. Diet and nutrition have been postulated as potential factors to combat the damaging effects of asthma. In particular, dietary antioxidants may play a role in alleviating the heightened oxidative stress in asthma. Although there are some observational and interventional studies that have shown protective effects of antioxidants in asthma, assessment of antioxidants in pregnancy are limited and there are no antioxidant intervention studies in asthmatic pregnancies on asthma outcomes. The aims of this paper are to (i) review the relationships between oxidative stress and dietary antioxidants in adults with asthma and asthma during pregnancy, and (ii) provide the rationale for which dietary management strategies, specifically increased dietary antioxidants, might positively impact maternal asthma outcomes. Improving asthma control through a holistic antioxidant dietary approach might be valuable in reducing asthma exacerbations and improving asthma management during pregnancy, subsequently impacting perinatal health.
Keywords: asthma
pregnancy
nutrition, antioxidants
oxidative stress
Rights: © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
DOI: 10.3390/nu5083212
Grant ID: http://purl.org/au-research/grants/nhmrc/510703
Published version: http://dx.doi.org/10.3390/nu5083212
Appears in Collections:Aurora harvest 4
Obstetrics and Gynaecology publications

Files in This Item:
File Description SizeFormat 
hdl_80376.pdfPublished version461.12 kBAdobe PDFView/Open
hdl_80376_version.pdfVersion information23.48 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.