Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/81135
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dc.contributor.authorSelth, L.en
dc.contributor.authorTownley, S.en
dc.contributor.authorGillis, J.en
dc.contributor.authorTilley, W.en
dc.contributor.authorButler, L.en
dc.date.issued2013en
dc.identifier.citationCirculating MicroRNAs. Methods and Protocols, 2013 / Ochiya, T. (ed./s), pp.235-246en
dc.identifier.isbn9781627034524en
dc.identifier.urihttp://hdl.handle.net/2440/81135-
dc.description.abstractMicroRNAs (miRNAs) derived from the cell-free fractions of blood are emerging as useful noninvasive markers of cancer. However, many tumors display significant molecular heterogeneity, which is likely to be reflected in the circulating miRNA fingerprints associated with that pathology. One strategy to minimize such heterogeneity is to employ genetically engineered mouse models of human cancer. Here, we describe a method to profile miRNAs in the serum of a mouse model of prostate cancer, TRansgenic Adenocarcinoma of Mouse Prostate (TRAMP), and discuss practical considerations for translating these potential biomarkers into a clinical setting.en
dc.description.statementofresponsibilityLuke A. Selth, Scott L. Townley, Joanna L. Gillis, Wayne D. Tilley, and Lisa M. Butleren
dc.language.isoenen
dc.publisherSpringeren
dc.rights© Springer Science+Business Media New York 2013en
dc.subjectCirculating; microRNA; Mouse model; Plasma; Prostate cancer; Serum; TRAMPen
dc.titleIdentification of prostate cancer-associated microRNAs in circulation using a mouse model of diseaseen
dc.typeBook chapteren
dc.identifier.rmid0020131329en
dc.identifier.doi10.1007/978-1-62703-453-1_19en
dc.publisher.placeUKen
dc.identifier.pubid18339-
pubs.library.collectionMedicine publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidSelth, L. [0000-0002-4686-1418]en
dc.identifier.orcidTilley, W. [0000-0003-1893-2626]en
dc.identifier.orcidButler, L. [0000-0003-2698-3220]en
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