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dc.contributor.authorWu, T.en
dc.contributor.authorRayner, C.en
dc.contributor.authorYoung, R.en
dc.contributor.authorHorowitz, M.en
dc.identifier.citationCurrent Opinion in Pharmacology, 2013; 13(6):928-934en
dc.description.abstractThe motility of the gastrointestinal (GI) tract is modulated by complex neural and hormonal networks; the latter include gut peptides released from enteroendocrine cells during both the interdigestive and postprandial periods. Conversely, it is increasingly recognised that GI motility is an important determinant of gut hormone secretion, in that the transit of luminal contents influences the degree of nutrient stimulation of enteroendocrine cells in different gut regions, as well as the overall length of gut exposed to nutrient. Of particular interest is the relationship between gallbladder emptying and enteroendocrine secretion. The inter-relationships between GI motility and enteroendocrine secretion are central to blood glucose homeostasis, where an understanding is fundamental to the development of novel strategies for the management of diabetes mellitus.en
dc.description.statementofresponsibilityTongzhi Wu, Christopher K Rayner, Richard L Young, Michael Horowitzen
dc.publisherElsevier Science Ltden
dc.rights© 2013 Elsevier Ltd. All rights reserved.en
dc.subjectGastrointestinal Tract; Animals; Humans; Gastrointestinal Hormones; Gastrointestinal Motility; Enteroendocrine Cellsen
dc.titleGut motility and enteroendocrine secretionen
dc.typeJournal articleen
pubs.library.collectionMedicine publicationsen
dc.identifier.orcidWu, T. [0000-0003-1656-9210]en
dc.identifier.orcidRayner, C. [0000-0002-5527-256X]en
dc.identifier.orcidYoung, R. [0000-0001-5116-4951]en
dc.identifier.orcidHorowitz, M. [0000-0002-0942-0306]en
Appears in Collections:Medicine publications

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