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https://hdl.handle.net/2440/8497
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Type: | Journal article |
Title: | Risk factors for the deterioration of glucose metabolism in polycystic ovary syndrome |
Author: | Wang, J. Norman, R. |
Citation: | Reproductive Biomedicine Online, 2004; 9(2):201-204 |
Publisher: | Reproductive Healthcare Ltd. |
Issue Date: | 2004 |
ISSN: | 1472-6483 1472-6491 |
Statement of Responsibility: | Jim Wang and Robert J. Norman |
Abstract: | Women with polycystic ovary syndrome (PCOS) have a high risk of abnormal glucose metabolism, which deteriorates gradually over time. This study was designed to assess contributing factors to the rate of deterioration of glucose metabolism over the 4- to 7-year follow-up period. The study group included 67 PCOS women who had normal glucose tolerance in the initial test in 1990-1992. There was a significant increase in both fasting and 2-h glucose concentrations, and body weight, over the follow-up period. The initial obesity, expressed as waist:hip ratio and BMI, was significantly related to the increase of glucose concentrations, while weight gain was not a significant factor. The overweight/obese PCOS women have a faster deterioration of glucose metabolism over the follow-up period than the non-obese ones. Moderate weight gain has no significant detrimental effect on the rate of deterioration of glucose metabolism. |
Keywords: | Diabetes glucose metabolism obesity PCOS BMI |
Description: | © Reproductive Biomedicine Online |
DOI: | 10.1016/S1472-6483(10)62130-X |
Published version: | http://www.rbmonline.com/4DCGI/Article/Detail?38%091%09=%201352 |
Appears in Collections: | Aurora harvest 4 Obstetrics and Gynaecology publications |
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