Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/8575
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | The influence of normal aging on oral-pharyngeal and upper esophageal sphincter function during swallowing |
Author: | Shaw, D. Cook, I. Gabb, M. Holloway, R. Simula, M. Panagopoulos, V. Dent, J. |
Citation: | American Journal of Physiology, 1995; 268(3 31-3):G389-G396 |
Publisher: | American Physiological Society |
Issue Date: | 1995 |
ISSN: | 0002-9513 2163-5773 |
Statement of Responsibility: | D. W. Shaw, I. J. Cook, M. Gabb, R. H. Holloway, M. E. Simula, V. Panagopoulos, and J. Dent |
Abstract: | The influence of aging on oral-pharyngeal swallowing was assessed by simultaneous manometry and videoradiography in 14 nondysphagic elderly individuals (mean age 76 yr) and 11 healthy, young controls (mean age 21 yr). Sphincter opening was diminished significantly in the elderly (P = 0.0001), but trans-sphincteric bolus flow rates were preserved. The increased impedance to trans-sphincteric bolus flow from reduced sphincter opening in the aged was reflected in a significant increase in hypopharyngeal intrabolus pressure (P = 0.003). Oral transit time was significantly prolonged in the aged (P = 0.01). The timing of upper esophageal sphincter (UES) manometric relaxation and of opening was significantly delayed in the aged (P = 0.0001), and this delay was comparable in magnitude to the prolongation in oral transit. Coordination of UES relaxation and opening with midpharyngeal contraction was not significantly affected by age. Deglutitive hyolaryngeal motion was not affected by age but was delayed by a duration equivalent to the prolongation in oral transit. We conclude that normal aging prolongs the oral-pharyngeal swallow that impairs UES opening but does not influence pharyngo-sphincteric coordination. |
Keywords: | Pharyngeal Muscles Esophagogastric Junction Humans Aging Deglutition Muscle Relaxation Pressure Adolescent Adult Aged Aged, 80 and over Middle Aged Female Male |
DOI: | 10.1152/ajpgi.1995.268.3.g389 |
Published version: | http://dx.doi.org/10.1152/ajpgi.1995.268.3.g389 |
Appears in Collections: | Aurora harvest Medicine publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.