Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/8593
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Validation of a novel luminal flow velocimeter with video fluoroscopy and manometry in the human esophagus |
Author: | Andrews, J. Nathan, H. Malbert, C.H. Verhagen, M. Gabb, M. Hebbard, G. Kilpatrick, S. MacDonald, S. Rayner, C. Doran, S. Omari, T. O'Young, E. Frisby, C. Fraser, R. Schoeman, M. Horowitz, M. Dent, J. |
Citation: | American Journal of Physiology: Gastrointestinal and Liver Physiology, 1999; 276(4):G886-G894 |
Publisher: | AMER PHYSIOLOGICAL SOC |
Issue Date: | 1999 |
ISSN: | 0193-1857 2163-5773 |
Statement of Responsibility: | J. M. Andrews, H. Nathan, C. H. Malbert, M. A. M. T. Verhagen, M. Gabb, G. S. Hebbard, D. Kilpatrick, S. MacDonald, C. K. Rayner, S. Doran, T. Omari, E. O'Young, C. Frisby, R. J. Fraser, M. Schoeman, M. Horowitz, and J. Dent |
Abstract: | There is currently no ideal method for concurrently assessing intraluminal pressures and flows in humans with high temporal resolution. We have developed and assessed the performance of a novel fiber-optic laser-Doppler velocimeter, mounted in a multichannel manometric assembly. Velocimeter recordings were compared with concurrent fluoroscopy and manometry following 50 barium swallows in healthy subjects. During these swallows, the velocimeter sensor was situated in either the proximal (24 swallows) or the distal (26 swallows) esophagus. It signaled intraluminal flow following 46 of 50 swallows. A greater mean number of deflections were recorded in the distal compared with the proximal esophagus (4. 3 vs. 2.4, P = 0.001). The maximal flow velocity recorded did not differ between the proximal and distal esophagus (76.7 vs. 73.8 mm/s). No velocimeter signals commenced after fluoroscopic lumen occlusion. The velocimeter signals were closely temporally related to fluoroscopic barium flow. Upward catheter movement on swallowing sometimes appeared to cause a velocimeter signal. Manometrically "normal" swallows were no different from "abnormal" swallows in the number and velocity of deflections recorded by the velocimeter. This novel instrument measures intraluminal flow velocity and pressures concurrently, thus enabling direct study of pressure-flow relationships. Flow patterns differed between the proximal and distal esophagus. |
Keywords: | intraluminal flow pressure-flow relationships laser-Doppler flow measurement |
DOI: | 10.1152/ajpgi.1999.276.4.g886 |
Published version: | http://dx.doi.org/10.1152/ajpgi.1999.276.4.g886 |
Appears in Collections: | Aurora harvest 4 Medicine publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.