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https://hdl.handle.net/2440/86971
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dc.contributor.author | Tajik, P. | - |
dc.contributor.author | van der Tuuk, K. | - |
dc.contributor.author | Koopmans, C. | - |
dc.contributor.author | Groen, H. | - |
dc.contributor.author | van Pampus, M. | - |
dc.contributor.author | van der Berg, P. | - |
dc.contributor.author | van der Post, J. | - |
dc.contributor.author | van Loon, A. | - |
dc.contributor.author | de Groot, C. | - |
dc.contributor.author | Kwee, A. | - |
dc.contributor.author | Huisjes, A. | - |
dc.contributor.author | van Beek, E. | - |
dc.contributor.author | Papatsonis, D. | - |
dc.contributor.author | Bloemenkamp, K. | - |
dc.contributor.author | van Unnik, G. | - |
dc.contributor.author | Porath, M. | - |
dc.contributor.author | Rijnders, R. | - |
dc.contributor.author | Stigter, R. | - |
dc.contributor.author | de Boer, K. | - |
dc.contributor.author | Scheepers, L. | - |
dc.contributor.author | et al. | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | BJOG: an International Journal of Obstetrics and Gynaecology, 2012; 119(9):1123-1130 | - |
dc.identifier.issn | 1470-0328 | - |
dc.identifier.issn | 1471-0528 | - |
dc.identifier.uri | http://hdl.handle.net/2440/86971 | - |
dc.description.abstract | Objective: To examine whether cervical favourability (measured by cervical length and the Bishop score) should inform obstetricians’ decision regarding labour induction for women with gestational hypertension or mild pre-eclampsia at term. Design: A post hoc analysis of the Hypertension and Pre-eclampsia Intervention Trial At Term (HYPITAT). Setting: Obstetric departments of six university and 32 teaching and district hospitals in the Netherlands. Population: A total of 756 women diagnosed with gestational hypertension or pre-eclampsia between 36 + 0 and 41 + 0 weeks of gestation randomly allocated to induction of labour or expectant management. Methods: Data were analysed using logistic regression modelling. Main outcome measures: The occurrence of a high-risk maternal situation defined as either maternal complications or progression to severe disease. Secondary outcomes were caesarean delivery and adverse neonatal outcomes. Results: The superiority of labour induction in preventing high-risk situations in women with gestational hypertension or mild pre-eclampsia at term varied significantly according to cervical favourability. In women who were managed expectantly, the longer the cervix the higher the risk of developing maternal high-risk situations, whereas in women in whom labour was induced, cervical length was not associated with a higher probability of maternal high-risk situations (test of interaction P = 0.03). Similarly, the beneficial effect of labour induction on reducing the caesarean section rate was stronger in women with an unfavourable cervix. Conclusion: Against widely held opinion, our exploratory analysis showed that women with gestational hypertension or mild pre-eclampsia at term who have an unfavourable cervix benefited more from labour induction than other women. Trial registration: The trial has been registered in the clinical trial register as ISRCTN08132825. | - |
dc.description.statementofresponsibility | Tajik P ... Mol B ... et al. | - |
dc.language.iso | en | - |
dc.publisher | Wiley | - |
dc.rights | © 2012 The Authors. Re-use of this article is permitted in accordance with the Terms and Conditions set out at http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms | - |
dc.source.uri | http://dx.doi.org/10.1111/j.1471-0528.2012.03405.x | - |
dc.subject | Bishop score; cervical length; expectant management; gestational hypertension; induction of labour; pre-eclampsia | - |
dc.title | Should cervical favourability play a role in the decision for labour induction in gestational hypertension or mild pre-eclampsia at term? An exploratory analysis of the HYPITAT trial | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1111/j.1471-0528.2012.03405.x | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Mol, B. [0000-0001-8337-550X] | - |
Appears in Collections: | Aurora harvest 2 Obstetrics and Gynaecology publications |
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